CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041441
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nesprin-2 
Protein Synonyms/Alias
  
Gene Name
 SYNE2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
192SKALDELKQSYLTLEubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1113 AA 
Protein Sequence
MLITQLPDIQ EKLHQLQMEK LPSRKAITEM ISWMNNVEHQ TSDEDSVHSP SSASQVKHLL 60
QKHKEFRMEM DYKQWIVDFV NQSLLQLSTC DVESKRYERT EFAEHLGEMN RQWHRVHGML 120
NRKIQHLEQL LESITESENK IQILNNWLEA QEERLKTLQK PESVISVQKL LLDCQDIENQ 180
LAIKSKALDE LKQSYLTLES GAVPLLEDTA SRIDELFQKR SSVLTQVNQL KTSMQSVLQE 240
WKIYDQLYDE VNMMTIRFWY CMEHSKPVVL SLETLRCQVE NLQSLQDEAE SSEGSWEKLQ 300
EVIGKLKGLC PSVAEIIEEK CQNTHKRWTQ VNQAIADQLQ KAQSLLQLWK AYSNAHGEAA 360
ARLKQQEAKF QQLANISMSG NNLAEILPPA LQDIKELQHD VQKTKEAFLQ NSSVLDRLPQ 420
PAESSTHMLL PGPLHSLQRA AYLEKMLLVK ANEFEFVLSQ FKDFGVRLES LKGLIMHEEE 480
NLDRLHQQEK ENPDSFLNHV LALTAQSPDI EHLNEVSLKL PLSDVAVKTL QNMNRQWIRA 540
TATALERCSE LQGIGLNEKF LYCCEKWIQL LEKIEEALKV DVANSLPELL EQQKTYKMLE 600
AEVSINQTIA DSYVTQSLQL LDTTEIENRP EFITEFSKLT DRWQNAVQGV RQRKGDVDGL 660
VRQWQDFTTS VENLFRFLTD TSHLLSAVKG QERFSLYQTR SLIHELKNKE IHFQRRRTTC 720
ALTLEAGEKL LLTTDLKTKE SVGRRISQLQ DSWKDMEPQL AEMIKQFQST VETWDQCEKK 780
IKELKSRLQV LKAQSEDPLP ELHEDLHNEK ELIKELEQSL ASWTQNLKEL QTMKADLTRH 840
VLVEDVMVLK EQIEHLHRQW EDLCLRVAIR KQEIEDRLNT WVVFNEKNKE LCAWLVQMEN 900
KVLQTADISI EEMIEKLQKD CMEEINLFSE NKLQLKQMGD QLIKASNKSR AAEIDDKLNK 960
INDRWQHLFD VIGSRVKKLK ETFAFIQQLD KNMSNLRTWL ARIESELSKP VVYDVCDDQE 1020
IQKRLAEQQP THGVQQKYYL MMTKNAMFIR EEVFQFFPMT MHFLFINVIF PKLGNCITII 1080
IKGQDSRDPT SLQATTALAG LYQLGRQGST ARY 1113 
Gene Ontology
  
Interpro
 IPR018159; Spectrin/alpha-actinin.
 IPR002017; Spectrin_repeat. 
Pfam
 PF00435; Spectrin 
SMART
 SM00150; SPEC 
PROSITE
  
PRINTS