UniProt Accession

 KV101_HUMAN; P01593 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 Ig kappa chain V-I region AG 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
103	RTFGQGTKLEIKR**	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 REGION 1 23 Framework-1.
 REGION 24 34 Complementarity-determining-1.
 REGION 35 49 Framework-2.
 REGION 50 56 Complementarity-determining-2.
 REGION 57 88 Framework-3.
 REGION 89 97 Complementarity-determining-3.
 REGION 98 107 Framework-4.
 DISULFID 23 88  

Keyword

 Bence-Jones protein; Complete proteome; Direct protein sequencing; Disulfide bond; Immunoglobulin domain; Immunoglobulin V region; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 108 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; NAS:UniProtKB.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0003823; F:antigen binding; NAS:UniProtKB.
 GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
 GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
 GO:0045087; P:innate immune response; TAS:Reactome. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr. 

Pfam

 PF07686; V-set 

SMART

 SM00406; IGv 

PROSITE

 PS50835; IG_LIKE 

PRINTS