Tag | Content |
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CPLM ID | CPLM-018092 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 483 |
Protein Synonyms/Alias | Zinc finger protein with KRAB and SCAN domains 16 |
Gene Name | ZNF483 |
Gene Synonyms/Alias | KIAA1962; ZKSCAN16 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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336 | SRRYNESKKPFSFHS | methylation | [1] | 337 | RRYNESKKPFSFHSD | methylation | [1] | 350 | SDLVLNRKEKTAGEK | methylation | [1] | 352 | LVLNRKEKTAGEKSR | methylation | [1] |
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Reference | [1] Large-scale global identification of protein lysine methylation in vivo. Cao XJ, Arnaudo AM, Garcia BA. Epigenetics. 2013 May 1;8(5):477-85. [ PMID: 23644510] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 52 134 SCAN box. DOMAIN 170 241 KRAB. ZN_FING 439 461 C2H2-type 1. ZN_FING 467 489 C2H2-type 2. ZN_FING 495 517 C2H2-type 3. ZN_FING 523 545 C2H2-type 4. ZN_FING 551 573 C2H2-type 5. ZN_FING 579 601 C2H2-type 6. ZN_FING 607 629 C2H2-type 7. ZN_FING 635 657 C2H2-type 8. ZN_FING 663 685 C2H2-type 9. ZN_FING 691 713 C2H2-type 10. ZN_FING 719 741 C2H2-type 11. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 744 AA |
Protein Sequence | MQAVVPLNKM TAISPEPQTL ASTEQNEVPR VVTSGEQEAI LRGNAADAES FRQRFRWFCY 60 SEVAGPRKAL SQLWELCNQW LRPDIHTKEQ ILELLVFEQF LTILPGEIRI WVKSQHPESS 120 EEVVTLIEDL TQMLEEKDPV SQDSTVSQEE NSKEDKMVTV CPNTESCESI TLKDVAVNFS 180 RGEWKKLEPF QKELYKEVLL ENLRNLEFLD FPVSKLELIS QLKWVELPWL LEEVSKSSRL 240 DESALDKIIE RCLRDDDHGL MEESQQYCGS SEEDHGNQGN SKGRVAQNKT LGSGSRGKKF 300 DPDKSPFGHN FKETSDLIKH LRVYLRKKSR RYNESKKPFS FHSDLVLNRK EKTAGEKSRK 360 SNDGGKVLSH SSALTEHQKR QKIHLGDRSQ KCSKCGIIFI RRSTLSRRKT PMCEKCRKDS 420 CQEAALNKDE GNESGEKTHK CSKCGKAFGY SASLTKHRRI HTGEKPYMCN ECGKAFSDSS 480 SLTPHHRTHS GEKPFKCDDC GKGFTLSAHL IKHQRIHTGE KPYKCKDCGR PFSDSSSLIQ 540 HQRIHTGEKP YTCSNCGKSF SHSSSLSKHQ RIHTGEKPYK CGECGKAFRQ NSCLTRHQRI 600 HTGEKPYLCN DCGMTFSHFT SVIYHQRLHS GEKPYKCNQC EKAFPTHSLL SRHQRIHTGV 660 KPYKCKECGK SFSQSSSLNE HHRIHTGEKP YECNYCGATF SRSSILVEHL KIHTGRREYE 720 CNECEKTFKS NSGLIRHRGF HSAE 744 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |