UniProt Accession

 B7Z7G5_HUMAN; B7Z7G5 

Genbank Protein ID

 AL359091; AK301986 

Genbank Nucleotide ID

 BAH13601.1 

Protein Name

 Probable tRNA pseudouridine synthase 2 

Protein Synonyms/Alias

 cDNA FLJ52131, highly similar to Homo sapiens TruB pseudouridine (psi) synthase homolog 2 (TRUB2), mRNA 

Gene Name

 TRUB2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
80	TVRGLLGKATDDFRE	ubiquitination	[1]
240	QVAAELEKSLSPGLD	ubiquitination	[2]
249	LSPGLDTKQLPSPGW	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 275 AA 

Protein Sequence

Gene Ontology

 GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
 GO:0006396; P:RNA processing; IEA:InterPro. 

Interpro

 IPR002501; PsdUridine_synth.
 IPR020103; PsdUridine_synth_cat_dom. 

Pfam

 PF01509; TruB_N 

SMART

  

PROSITE

  

PRINTS