UniProt Accession

 TOM34_MOUSE; Q9CYG7; A2A5N5; A2A5N6; Q3THD0; Q812F1; Q812F2; Q9D059 

Genbank Protein ID

 AB087254; AB087254; AK011786; AK017699; AK075873; AK168329; AL591542; AL591542; BC018278 

Genbank Nucleotide ID

 BAC57494.1; BAC57495.1; BAB27840.1; BAB30882.1; BAC36020.1; BAE40267.1; CAM20764.1; CAM20765.1; AAH18278.1 

Protein Name

 Mitochondrial import receptor subunit TOM34 

Protein Synonyms/Alias

 Translocase of outer membrane 34 kDa subunit 

Gene Name

 Tomm34 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
86	ALVPFSIKPLLRRAS	acetylation	[1]
255	KDCTEALKLDGKNVK	acetylation	[1]
278	YKALKDYKSSLSDIS	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state (By similarity). 

Sequence Annotation

 REPEAT 9 42 TPR 1.
 REPEAT 51 84 TPR 2.
 REPEAT 85 118 TPR 3.
 REPEAT 193 226 TPR 4.
 REPEAT 227 260 TPR 5.
 REPEAT 261 294 TPR 6.
 MOD_RES 186 186 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Reference proteome; Repeat; TPR repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 309 AA 

Protein Sequence

Gene Ontology

 GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0006626; P:protein targeting to mitochondrion; IEA:Compara. 

Interpro

 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 

Pfam

 PF00515; TPR_1 

SMART

 SM00028; TPR 

PROSITE

 PS50005; TPR
 PS50293; TPR_REGION 

PRINTS