CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027585
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Ugt2b1 
Protein Synonyms/Alias
 UDP glucuronosyltransferase 2 family, polypeptide B1 
Gene Name
 Ugt2b1 
Gene Synonyms/Alias
 mCG_1792 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
103NWTYELKKLPFWTSYubiquitination[1]
112PFWTSYSKLQKISSEubiquitination[1]
115TSYSKLQKISSEYSDubiquitination[1]
135CKAVVWNKSLMKKLQacetylation[2]
135CKAVVWNKSLMKKLQubiquitination[1]
343VLWRFDGKKPDTLGSacetylation[2, 3]
343VLWRFDGKKPDTLGSubiquitination[1]
344LWRFDGKKPDTLGSNacetylation[3]
356GSNTRLYKWIPQNDLubiquitination[1]
440VINDPSYKENAMRLSubiquitination[1]
456IHHDQPMKPLDRAVFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 529 AA 
Protein Sequence
MSMKQASVFL LIQFICYIRP GACGKVLVWP TEYSHWINMK IILDELVQRG HDVTVLISSA 60
SILIGPSNES SINFEIYSAP LSKDDLEYAF EKWVGNWTYE LKKLPFWTSY SKLQKISSEY 120
SDMIESFCKA VVWNKSLMKK LQGSKFDVVL ADALVPCGEL LSELLKTPLV YSLRFCPGYK 180
CEKYSGGLPL PPSYVPVVLS ELSDHMTFAE RVKNMLQVLL FDFWFQTFNE KSWNQFYSDV 240
LGRPTTLTEM MGKADIWLVR TFWDLKFPHP FLPNFDFVGG LHCKPAKPLP KEMEEFVQSS 300
GEHGVVVFSL GSMVKNIKEE KANVVASALA QIPQKVLWRF DGKKPDTLGS NTRLYKWIPQ 360
NDLLGHPKTK AFIAHGGTNG IYEAIYHGIP IVGIPLFGDQ PDNINHIVAK GAAVRVDFDT 420
MSTTDLLTAL KTVINDPSYK ENAMRLSRIH HDQPMKPLDR AVFWIEYVMR NKGAKHLRPA 480
LHDLTWFQYH SLDVIGFLLV CVVAVVFIIA KCCLFCCHKT ANMGKKKKE 529 
Gene Ontology
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0015020; F:glucuronosyltransferase activity; IEA:Compara.
 GO:0070980; P:biphenyl catabolic process; IEA:Compara.
 GO:0071361; P:cellular response to ethanol; IEA:Compara.
 GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Compara.
 GO:0071378; P:cellular response to growth hormone stimulus; IEA:Compara.
 GO:0071394; P:cellular response to testosterone stimulus; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara. 
Interpro
 IPR002213; UDP_glucos_trans. 
Pfam
 PF00201; UDPGT 
SMART
  
PROSITE
 PS00375; UDPGT 
PRINTS