| Tag | Content |
|---|
| CPLM ID | CPLM-013423 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytosolic phospholipase A2 epsilon |
Protein Synonyms/Alias | cPLA2-epsilon; Phospholipase A2 group IVE |
Gene Name | Pla2g4e |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 91 | TVRIIGMKNVRQADI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. |
Sequence Annotation | DOMAIN 68 168 C2.
DOMAIN 332 875 PLA2c.
ACT_SITE 420 420 Nucleophile (By similarity).
ACT_SITE 708 708 Proton acceptor (By similarity). |
Keyword | Alternative splicing; Calcium; Complete proteome; Cytoplasm; Hydrolase; Lipid degradation; Lipid metabolism; Lysosome; Membrane; Metal-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 875 AA |
Protein Sequence | MQSIPHSDEA DVAGMTHASE GHHGLGTSML VPKNPQGEED SKLGRNCSGF EDAQDPQTAV 60
PSSPLLSMAS CSSQEGSSPC HLLTVRIIGM KNVRQADILS QTDCFVTLWL PTASQKKLKT 120
RTISNCLHPE WDESFTFQIQ TQVKNVLELS VCDEDTLTQN DHLLTVLYDL SKLCLRNKTH 180
VKFPLNPEGM EELEVEFLLE ENFSSSETLI TNGVLVSRQV SCLEVHAESR RPRKRKKNKD 240
LLVMVTDSFE NTQRVPPCQE PCYPNSACFH YPKYSQPQLY AEAPKSHCNF RLCCCGTHRN 300
DPVCQPLNCL SDGQVTTLPV GENYELHMKS SPCSDTLDVR LGFSLCQEEV EFVQKRKMVV 360
AKTLSQMLQL EEGLHEDEVP IIAIMATGGG TRSMVSLYGH LLGLQKLNFL DASTYITGLS 420
GATWTMATLY SDPEWSSKNL ETVVFEARRH VVKDKMPALF PDQLYKWRED LQKHSQEGYK 480
TTFTDFWGKL IEYSLGDKKN ECKLSDQRAA LCRGQNPLPI YLTINVKDDV SNQDFREWFE 540
FSPYEVGMQK YGAFIPSELF GSEFFMGRLM KRIPEPEMCY MLGLWSSIFS LNLLDAWNLS 600
HTSEEFFYRW TRERLHDIED DPILPEIPRC DDNPLETTVV IPTTWLSNTF REILTRRPFV 660
SEFHNFLYGM QLHTDYLQNR QFSMWKDTVL DTFPNQLTQF AKHLNLLDTA FFVNSSYAPL 720
LRPERKVDLI IHLNYCAGSQ TKPLKQTCEY CTEQKIPFPS FSILEDDNSL KECYVMENPQ 780
EPDAPIVAYF PLISDTFQKY KAPGVERSPD ELELGQLNIY GPKSPYATKE LTYTEAAFDK 840
LVKLSEYNIL NNRDKLIQAL RLAMEKKRMR SQCPS 875 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |