UniProt Accession

 ASSY_BACSU; O34347 

Genbank Protein ID

 AF008220; AL009126 

Genbank Nucleotide ID

 AAC00320.1; CAB14905.1 

Protein Name

 Argininosuccinate synthase 

Protein Synonyms/Alias

 Citrulline--aspartate ligase 

Gene Name

 argG 

Gene Synonyms/Alias

 BSU29450 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
108	KLVEIAEKEDAQAIA	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

  

Sequence Annotation

 NP_BIND 10 18 ATP (By similarity).
 BINDING 87 87 Citrulline (By similarity).
 BINDING 117 117 ATP; via amide nitrogen (By similarity).
 BINDING 119 119 Aspartate (By similarity).
 BINDING 123 123 Aspartate (By similarity).
 BINDING 123 123 Citrulline (By similarity).
 BINDING 124 124 Aspartate (By similarity).
 BINDING 127 127 Citrulline (By similarity).
 BINDING 175 175 Citrulline (By similarity).
 BINDING 260 260 Citrulline (By similarity).
 BINDING 272 272 Citrulline (By similarity).  

Keyword

 Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 403 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004055; F:argininosuccinate synthase activity; IEA:HAMAP.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0006526; P:arginine biosynthetic process; IEA:HAMAP. 

Interpro

 IPR001518; Arginosuc_synth.
 IPR018223; Arginosuc_synth_CS.
 IPR023434; Arginosuc_synth_type_1_subfam.
 IPR024074; AS_cat/multimer_dom_body.
 IPR014729; Rossmann-like_a/b/a_fold. 

Pfam

 PF00764; Arginosuc_synth 

SMART

  

PROSITE

 PS00564; ARGININOSUCCIN_SYN_1
 PS00565; ARGININOSUCCIN_SYN_2 

PRINTS