CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016571
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Large neutral amino acids transporter small subunit 3 
Protein Synonyms/Alias
 L-type amino acid transporter 3; Solute carrier family 43 member 1 
Gene Name
 Slc43a1 
Gene Synonyms/Alias
 Lat3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
6**MAPTLKQAYRRRWubiquitination[1]
555TNLVDPQKVLNTSKVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine (By similarity). 
Sequence Annotation
 MOD_RES 265 265 Phosphoserine.
 CARBOHYD 54 54 N-linked (GlcNAc...) (Potential).
 CARBOHYD 57 57 N-linked (GlcNAc...).
 CARBOHYD 396 396 N-linked (GlcNAc...) (Potential).
 CARBOHYD 558 558 N-linked (GlcNAc...) (Potential).  
Keyword
 Amino-acid transport; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 564 AA 
Protein Sequence
MAPTLKQAYR RRWWMACTAV VENLFFSAVL LGWASLLIML KKEGFYSSLC PAENRTNTTQ 60
DEQHQWTSCD QQEKMLNLGF TIGSFLLSAT TLPLGILMDR FGPRPLRLVG SACFAASCTL 120
MALASRDTEV LSPLIFLALS LNGFAGICLT FTSLTLPNMF GNLRSTFMAL MIGSYASSAI 180
TFPGIKLIYD AGVPFTVIMF TWSGLACLIF LNCALNWPAE AFPAPEEVDY TKKIKLIGLA 240
LDHKVTGDRF YTHVTIVGQR LSQKSPSLEE GADAFISSPD IPGTSEETPE KSVPFRKSLC 300
SPIFLWSLVT MGMTQLRVIF YMGAMNKILE FIVTGGKERE TNEQRQKVEE TVEFYSSIFG 360
VMQLLCLLTC PLIGYIMDWR IKDCVDAPTE GTLNENASFG DARDGASTKF TRPRYRKVQK 420
LTNAINAFTL TNILLVGFGI ACLIKNLHLQ LLAFVLHTIV RGFFHSACGG LYAAVFPSNH 480
FGTLTGLQSL ISAVFALLQQ LLFMAMVGPL HGDPFWVNLG LLLLSFLGFL LPSYLYYYRS 540
RLQREYATNL VDPQKVLNTS KVAT 564 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0015179; F:L-amino acid transmembrane transporter activity; IDA:MGI.
 GO:0015175; F:neutral amino acid transmembrane transporter activity; ISS:UniProtKB. 
Interpro
 IPR027199; LAT3.
 IPR011701; MFS.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR027192; SLC43. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
  
PRINTS