UniProt Accession

 C9JHS6_HUMAN; C9JHS6 

Genbank Protein ID

 AC118344 

Genbank Nucleotide ID

  

Protein Name

 RAC-beta serine/threonine-protein kinase 

Protein Synonyms/Alias

  

Gene Name

 AKT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
142	EMEVAVSKARAKVTM	ubiquitination	[1]
146	AVSKARAKVTMNDFD	ubiquitination	[1]
156	MNDFDYLKLLGKGTF	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 184 AA 

Protein Sequence

Gene Ontology

 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:Compara.
 GO:0032859; P:activation of Ral GTPase activity; IEA:Compara.
 GO:0008286; P:insulin receptor signaling pathway; IEA:Compara.
 GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Compara.
 GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IEA:Compara.
 GO:0072659; P:protein localization to plasma membrane; IEA:Compara.
 GO:0046328; P:regulation of JNK cascade; IEA:Compara. 

Interpro

 IPR011009; Kinase-like_dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS. 

Pfam

 PF00169; PH 

SMART

 SM00233; PH 

PROSITE

 PS50003; PH_DOMAIN
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM 

PRINTS