CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014696
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kelch-like protein 36 
Protein Synonyms/Alias
  
Gene Name
 Klhl36 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MEASKQMRVSRPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). 
Sequence Annotation
 DOMAIN 45 112 BTB.
 DOMAIN 147 249 BACK.
 REPEAT 294 343 Kelch 1.
 REPEAT 344 395 Kelch 2.
 REPEAT 396 442 Kelch 3.
 REPEAT 444 491 Kelch 4.
 REPEAT 492 544 Kelch 5.
 REPEAT 545 593 Kelch 6.  
Keyword
 Complete proteome; Kelch repeat; Reference proteome; Repeat; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 613 AA 
Protein Sequence
MEASKQMRVS RPYKISESSK VYHWPGHSTT VLQRLNEQRL HGLFCDVVLV VEEQQVPAHR 60
NLLAVCSDYF NSMFTLGMRE AFQKEVELVG TSYVGLKAVV DFLYSSELEL DGSNIDYILE 120
TAHLLQIWTV VDFCCEYLEQ EVSEDNYLYL QELASIYSLK RLDAFIDSFV LNHFSTLSFT 180
PDFLQTVSVQ KLCIYLSSGQ VQHTWEYDLL QAALQWLTQQ PEREVHTCRV LENIRFPLFP 240
EDILLQRVKL AMCSLLPSEA NGEGFVEEAM HYHNSLVAQP VLQTKRTLLR SEECLLFVGG 300
EVSERCLELS DDTCYLDTKN EQWVKETSLP ARRSHHCVAV LGGFIFVAGG SFSRDNGGNA 360
ASNLLYRYDP RRKQWIKVAS MNQRRVDFYL ASIEDMLVAV GGRNENGALS SVETYSPKTN 420
SWTYVAGLPR FTYGHAGTIY KDFVYISGGH DYQIGPYRKN LLCYDHRTDV WEERRPMTTA 480
RGWHSMCSLG DSIYSIGGSD DHMESMERFD VLGVEAYSPQ CNQWTRVAPL LQANSESGVA 540
VWQGRIYILG GYSWESTAFS RAVQVYDREA NRWSRGPDLP NAIAGVSACV CALNPRLEEK 600
KKKNKDKRQD RGQ 613 
Gene Ontology
 GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. 
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR015916; Gal_Oxidase_b-propeller.
 IPR017096; Kelch-like_gigaxonin.
 IPR006652; Kelch_1. 
Pfam
 PF07707; BACK
 PF00651; BTB
 PF01344; Kelch_1 
SMART
 SM00875; BACK
 SM00225; BTB
 SM00612; Kelch 
PROSITE
 PS50097; BTB 
PRINTS