UniProt Accession

 MAK16_YEAST; P10962; D6VPJ3 

Genbank Protein ID

 J03852; U12980; BK006935 

Genbank Nucleotide ID

 AAA34752.1; AAC05007.1; DAA06963.2 

Protein Name

 Protein MAK16 

Protein Synonyms/Alias

 Maintenance of killer protein 16 

Gene Name

 MAK16 

Gene Synonyms/Alias

 YAL025C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
49	SCPLANSKYATVKCD	ubiquitination	[1]
157	RKALVAAKIEKAIEK	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Its role might be as part of the apparatus concerned with the nuclear events of the cell cycle. 

Sequence Annotation

 REPEAT 213 220 1.
 REPEAT 222 229 2.
 REGION 213 229 2 X 8 AA repeats.
 REGION 251 264 7 X 2 AA repeats of S-[DE].
 MOTIF 139 144 Nuclear localization signal (Potential).
 MOTIF 282 287 Nuclear localization signal (Potential).  

Keyword

 Cell cycle; Complete proteome; Nucleus; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 306 AA 

Protein Sequence

Gene Ontology

 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. 

Interpro

 IPR006958; Mak16. 

Pfam

 PF04874; Mak16 

SMART

  

PROSITE

  

PRINTS