UniProt Accession

 Q5VT94_HUMAN; Q5VT94 

Genbank Protein ID

 AC022389; AL603756 

Genbank Nucleotide ID

  

Protein Name

 Growth hormone-inducible transmembrane protein 

Protein Synonyms/Alias

  

Gene Name

 GHITM 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
23	VFHPAFTKASPVVKN	ubiquitination	[1]
29	TKASPVVKNSITKNQ	ubiquitination	[1]
34	VVKNSITKNQWLLTP	ubiquitination	[1]
63	GRTGQELKEAALEPS	ubiquitination	[1, 2, 3]
76	PSMEKIFKIDQMGRW	ubiquitination	[1]
101	VIWPQYVKDRIHSTY	ubiquitination	[3]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 325 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara. 

Interpro

 IPR010539; Bax_inhibitor-1.
 IPR006214; Bax_inhibitor_1-related. 

Pfam

 PF01027; Bax1-I
 PF12811; BaxI_1 

SMART

  

PROSITE

  

PRINTS