UniProt Accession

 COX5B_RAT; P12075 

Genbank Protein ID

 D10952; D10951; BC083179; X14208 

Genbank Nucleotide ID

 BAA01744.1; BAA01743.1; AAH83179.1; CAA32425.1 

Protein Name

 Cytochrome c oxidase subunit 5B, mitochondrial 

Protein Synonyms/Alias

 Cytochrome c oxidase polypeptide Vb; Cytochrome c oxidase subunit VIA* 

Gene Name

 Cox5b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
68	PYNMLPPKAASGTKE	acetylation	[1]
74	PKAASGTKEDPNLVP	acetylation	[1]
86	LVPSVSNKRIVGCIC	acetylation	[1]
121	PNCGTHYKLVPYQMV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. 

Sequence Annotation

 METAL 91 91 Zinc (By similarity).
 METAL 93 93 Zinc (By similarity).
 METAL 113 113 Zinc (By similarity).
 METAL 116 116 Zinc (By similarity).  

Keyword

 Complete proteome; Direct protein sequencing; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 129 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0004129; F:cytochrome-c oxidase activity; TAS:RGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0043434; P:response to peptide hormone stimulus; IEP:RGD. 

Interpro

 IPR002124; Cyt_c_oxidase_su5b.
 IPR020893; Cyt_c_oxidase_su5b_Zn_BS. 

Pfam

 PF01215; COX5B 

SMART

  

PROSITE

 PS00848; COX5B_1
 PS51359; COX5B_2 

PRINTS