CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027987
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nup358 
Protein Synonyms/Alias
  
Gene Name
 Nup358 
Gene Synonyms/Alias
 CG11856; Dmel_CG11856 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
38AVARLYMKVQEYPKAacetylation[1]
1264SESPFSFKTQVAKAAacetylation[1]
1332GEEGEDIKFTSRAKLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2695 AA 
Protein Sequence
MFTTRKEVDA HVHKMLGKLQ PGRERDIKGL AVARLYMKVQ EYPKAIEYLN GYLRVRDDAV 60
GHNMIATCYS RLNPPDVTEA LQHYQRSIQI DPRQSEVVID ACELLVKENN ASITECARYW 120
LDQANSLDLS GNKQVFNLRM RVNLADSNGE RDDTSGGDGE QNTLEILMYK ELQARPQDVN 180
IRIQLLRSYV EKMKIDQAFN YALKTELESK NCTSQSNEWY EQIWMVLFKI EMAKDVKKNW 240
RFWHFALHTL DRLVQLSLEG SGLADSSKQL FRLDQYLFKF STSIERSGDA PQRDLHQACI 300
DHFTGQLLLH AVTLIFKREV LANKNKWMST LRSALPLLLL GYQVRPIDDS STNQWIKHCD 360
AEQKQLIQMW RPQGAFRCAQ LGRTLLGCLD RSQMEIKNDR ENAEFDENKN SGNSMPGLFA 420
DSEELLASAH QQCLDKSWRS QIYQQLFTHA EHKLKDTSSH LVRNLRLQLP LFEWPNLAHI 480
ENYELQALVL PPHSLAQHVY LALGTDPNKL GDAPRVVFYE GFQRDVKQNL NYCGQDSISQ 540
VDVDLYLYAT TIQTRRKLQI QREVYDSSNL GNRNAAARPH MMPFANLVGQ LGAPEQSNWW 600
DLVVRLNSNQ LITEGNRAEQ RAQLQHGLEA VRGVNGPKAD AIIIFQLGKI LNSRSDRSSL 660
EARIDTLYRQ GFSILRHQHN QQMESYVRVF KYGSAGSTAA WQDLQSLAEE AVTYFSEKMF 720
RIGQYEQFLD EVRGLHLPMA YFLQSEACHH LEESSKLPRT SRDRYSERRR ECLQKTQKLI 780
KNDDKHPLIA AMHRHQQDRN SRGIDNSFGS PDVHNNSSAY EDAEDDFYSH AAFSANRSRR 840
QLEVTPVTPI VMAQPSQEME QAVKQISKSL CVLKDDVSVG MEAMRQDIKV LTEKFTGLED 900
LLKKIKISSR DTPTRDVDPA AALGLDDLFI IEDALAEHQQ QQQHQQQQSH NQGAIHPVVP 960
NPYTSGFYNG MPNTPSAQER FLQGPYGSPM FNQNQMYNYY AAQAQAQAQA QFLRTPPAPG 1020
SIPPPNMFGP RNPNFGLPSM FPPPTVPSVA PYIDAMGNFT QPPPSLIPPP AQPAAPPAPL 1080
NILESKPVVA LPTPGFFNTT TPVFGASPIQ VPQSKPLTVP TVPIPSTAPA PPIAGTVNPP 1140
ATTAVPPPVH IPQVAPSVPA QPPAPAPVSV PSMFNRALNN QPVEKEPPAN VVITSSDPLP 1200
KPTTASVQPT LSVTIPAQHI KPSLVQAPEQ PAQSAQPAQP SVSGVGSLSF NFGSKSSESP 1260
FSFKTQVAKA AAEKQKEQEE AEQNQSGATD PNKTLPQDTS ADDYDPRPDF KPIIPLPDEV 1320
EVRTGEEGED IKFTSRAKLF RYVDKEWKER GTGVIKILCD KATGVSRVLM RRDQTHKVCA 1380
NHTITADITI NVANQDKDKK SLLWAANDFA DEQVTLERFL VRFKTGELAE EFRVAFTKAS 1440
EAAKSKETVK PTVNTAEKGS TATAPAAFKS FVTSTPAANS LINKPQEQTK TQPNPDPPAT 1500
AAKSLFGTLS VSAAPATSAP ASATPFASFS FTPNGSSGFG TSTASPFGNL SFGTASAVGS 1560
GNNTTLFTTA LIKDNTVQGK TLQQESQLNK SNSSDAEEEY VPTAQFVPVI ALPDIVEVVT 1620
GEENEDVLFE HRAKLLRWDK EANEWKERGL GNMKLLRDRT DPNKVRLLMR REQVHKLCCN 1680
QRLLPETKFT YATNCKAAVT WGAQDYSDEE LTTALLAVRF KSQDICQQFL EAVQKAQQSI 1740
GNEPKKEEVP SAAGEKEKPI KGFGDAFKPK AGSWNCQACY TNNGQDQLYC LACQEPKDAT 1800
VPPKQSGLDQ GNALNLTTSS SNKFSFGFAS SATLPATGGF SFGGATQPKE KPAVAVVTAS 1860
ASAPTSVQTA ALGFGKSSMT SGFGDAFKPA VGSWSCSACY VNNPGESLYC SACDAPKNDT 1920
VPQKEKSLGS GLNLPPTSKF SFGFGAAAAG DKDQAGDGAT FNFAAMPAAV APTTSIGSSS 1980
FTFSMTKPKP DQQQPNSTAA KEDEDNDSQE VEEEENNTYF SPVIPLPDKI DVKTGEEDEE 2040
LLYVHKAKLY RLNESDWKER GLGDVKILRH RQTKKLRVVM RREQVFKICL NHVLNENVVY 2100
REKTETSWMF AVHDFSEGES VLERFTLRFK NKEVAQGFME AIKNALNETA KPIEDSPVVG 2160
SVSQSTEANK PSQKNDGAAK SRGGESEVLD VGKTSSPLAK PNDYQTPATI LFKGSSLSRN 2220
NSSASEASKT PSSAFIFGST DKSEPGKDAG PLANLQKLAS GEGQGNVLGS IFRSGSSNEN 2280
SSDGSVKFFF GGGNKAAEQQ KKDSSESVFG GNKADSQSPA TQEAPKLAFG GIAAPVFGDA 2340
NPFGGHKVNL QKSDGKEEPK SIIGGTPLLF GGSNAFGIPK IETQSPAKDF VFGSAPAFGQ 2400
MATFSFTAAK NEKEKDITSN NTTDLKAEGK EKKELVPETT STFADLAKTG STFADLASNP 2460
GGTFADLANK TGNDFANLSA NSQGTTVGFN KSAGGGFYNL THQNAFKNFE SPQATEECDD 2520
DGDATTDDNY DPHYDAIVEL PDEIVVTTGE ENETKLFGER AKLYRYDAES KQWKERGVGE 2580
IKVLEHPELQ TFRLIMRQEQ IHKLVLNMNI SASLQMDYMN AQMKSFLWAG YNYAVDAEGK 2640
VDTEGVLERL ACRFAKEEIA SEFLNTVNSC IKRAKALQGD EENKNDDAPE EQASS 2695 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006607; P:NLS-bearing substrate import into nucleus; IMP:FlyBase.
 GO:0007184; P:SMAD protein import into nucleus; IMP:FlyBase. 
Interpro
 IPR011993; PH_like_dom.
 IPR000156; Ran_bind_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR001876; Znf_RanBP2. 
Pfam
 PF00638; Ran_BP1
 PF00641; zf-RanBP 
SMART
 SM00160; RanBD
 SM00547; ZnF_RBZ 
PROSITE
 PS50196; RANBD1
 PS50293; TPR_REGION
 PS01358; ZF_RANBP2_1
 PS50199; ZF_RANBP2_2 
PRINTS