UniProt Accession

 TBPL1_HUMAN; P62380; A8K8F5; O95753; Q9BWD5; Q9Z2Z0 

Genbank Protein ID

 AB020881; AF130312; AF136570; AK292320; AK313645; AL035699; CH471051; CH471051; BC000381; BC017559 

Genbank Nucleotide ID

 BAA75218.1; AAD24800.1; AAD28785.1; BAF85009.1; BAG36402.1; CAB43704.1; EAW47995.1; EAW47996.1; AAH00381.1; AAH17559.1 

Protein Name

 TATA box-binding protein-like protein 1 

Protein Synonyms/Alias

 TBP-like protein 1; 21 kDa TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-related factor 2; TBP-related factor 2; TBP-like factor; TBP-related protein 

Gene Name

 TBPL1 

Gene Synonyms/Alias

 TLF; TLP; TLP21; TRF2; TRP 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
41	EGANVIYKRDVGKVL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Does not bind the TATA box. Has DNA-binding ability. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; DNA-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 186 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005672; C:transcription factor TFIIA complex; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003713; F:transcription coactivator activity; TAS:UniProtKB.
 GO:0001675; P:acrosome assembly; IEA:Compara.
 GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro.
 GO:0006235; P:dTTP biosynthetic process; IEA:Compara.
 GO:0007289; P:spermatid nucleus differentiation; IEA:Compara.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB. 

Interpro

 IPR012295; Beta2_adaptin/TBP_C_dom.
 IPR000814; TBP. 

Pfam

 PF00352; TBP 

SMART

  

PROSITE

 PS00351; TFIID 

PRINTS

 PR00686; TIFACTORIID.