CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035475
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nudix (Nucleoside diphosphate linked moiety X)-type motif 12 (Predicted) 
Protein Synonyms/Alias
 Protein Nudt12 
Gene Name
 Nudt12 
Gene Synonyms/Alias
 Nudt12_predicted; rCG_55382 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
453AIAHQLIKHWVGMNPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MSSVKRNPKR EIISELHSSA AEGDVAKLAG ILSHSPSLLN ETSENGWTAL MYAARNGHPD 60
AVQFLLEKGC DRSSVNKSRQ TALDIAVFWG YKHIANLLAN AKGGKKPWFL TSDVDGCENY 120
FSRTLLDRRS DKRTNSDWLQ AKESHPTTVY ILFSDLNPLV TLGGNKESSQ QPEVRLCQLN 180
YADIKDYLAQ PEKITLVFLG VELEMRKGSH AHAGGVPEGE EDGLVAWFVL GIEPGAAEEF 240
KQRHENCYFL HPPMPALLQL KEKEAGVVAQ ARSVLAWHSR YKFCPTCGST TKIEEGGYKR 300
VCVRENCPSL HGVHNTSYPR VDPVVIMQVI HPDGTKCLLG RQKRFPPGMF TCLAGFIEPG 360
ETIEDAVRRE VGEESGVKVG HVQYVSCQPW PMPSSLMIGC LAVAVSTEIK VDKNEIEDAR 420
WFTREQVVDV LTKGKQQAFF VPPSRAIAHQ LIKHWVGMNP SL 462 
Gene Ontology
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR015375; NADH_PPase-like_N.
 IPR020084; NUDIX_hydrolase_CS.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like.
 IPR015376; Znr_NADH_PPase. 
Pfam
 PF12796; Ank_2
 PF00293; NUDIX
 PF09296; NUDIX-like
 PF09297; zf-NADH-PPase 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS51462; NUDIX
 PS00893; NUDIX_BOX 
PRINTS