UniProt Accession

 B4DSY9_HUMAN; B4DSY9 

Genbank Protein ID

 AL611942; AK299980 

Genbank Nucleotide ID

 BAG61801.1 

Protein Name

 U4/U6 small nuclear ribonucleoprotein Prp3 

Protein Synonyms/Alias

 cDNA FLJ50652, highly similar to U4/U6 small nuclear ribonucleoprotein Prp3 

Gene Name

 PRPF3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
117	VELKDQTKPTPLILD	acetylation	[1]
163	EQFKQQLKEKPSEDM	ubiquitination	[2]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Ribonucleoprotein; Viral nucleoprotein; Virion. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 281 AA 

Protein Sequence

Gene Ontology

 GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:UniProtKB-KW.
 GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro. 

Interpro

 IPR013881; Pre-mRNA_splic_Prp3.
 IPR027104; Prp3. 

Pfam

 PF08572; PRP3 

SMART

  

PROSITE

  

PRINTS