CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase 
Protein Synonyms/Alias
  
Gene Name
 rpoB1 
Gene Synonyms/Alias
 SSO0227 
Created Date
 July 27, 2013 
Organism
 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322  
NCBI Taxa ID
 273057 
Lysine Modification
Position
Peptide
Type
References
12INERIVEKTLYEMGVmethylation[1]
311GVRGYKGKEYYRLLEmethylation[1]
349PRFLQEFKELSPEQAmethylation[1]
Reference
 [1] Extensive lysine methylation in hyperthermophilic crenarchaea: potential implications for protein stability and recombinant enzymes.
 Botting CH, Talbot P, Paytubi S, White MF.
 Archaea. 2010 Aug 5;2010. [PMID: 20811616] 
Functional Description
  
Sequence Annotation
 METAL 586 586 Zinc.
 METAL 589 589 Zinc.
 METAL 604 604 Zinc.  
Keyword
 3D-structure; Complete proteome; DNA-directed RNA polymerase; Metal-binding; Nucleotidyltransferase; Reference proteome; Transcription; Transferase; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 649 AA 
Protein Sequence
MLYGINERIV EKTLYEMGVV PVEEVIRRVT EGGEDQNEYL KWSKVILNGR LIGYYQDGGE 60
LANKIRERRR KGEISDEVNV GHIVTDFINE VHVNCDSGRV RRPLIIVSNG NPLVTIEDIE 120
KLESGAITFD DLVRQGKIEY LDAEEEENAY VALEPNDLTP DHTHLEIWSP AILGITASII 180
PYPEHNQSPR NTYQSAMAKQ ALGLYAANYQ LRTDTRAHLL HYPQRPLVQT RALDIIGYTN 240
RPAGNNAILA VMSFTGYNME DSIIMNRSSV ERGMYRSTFF RLYSTEEVKY PGGQEDKIVM 300
PEAGVRGYKG KEYYRLLEDN GVVSPEVEVK GGDVLIGKVS PPRFLQEFKE LSPEQAKRDT 360
SIVTRHGEMG IVDLVLITET AEGNKLVKVR VRDLRIPTIG DKFASRHGQK GVIGMLIPQV 420
DMPYTVKGVV PDIILNPHAL PSRMTLGQIM EGIAGKYAAL SGNIVDATPF YKTPIEQLQN 480
EILRYGYLPD ATEVVYDGRT GQKIKSRIYF GVVYYQKLHH MVADKLHARA RGPVQILTRQ 540
PTEGRAREGG LRFGEMERDC LIGFGTAMLL KDRLLDNSDR TMIYVCDQCG YIGWYDKNKN 600
KYVCPIHGDK SNLFPVTVSY AFKLLIQELM SMIISPRLVL EDKVGLSGG 649 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0032549; F:ribonucleoside binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR015712; DNA-dir_RNA_pol_su2.
 IPR007120; DNA-dir_RNA_pol_su2_6.
 IPR007121; RNA_pol_bsu_CS.
 IPR007646; RNA_pol_Rpb2_4.
 IPR007647; RNA_pol_Rpb2_5.
 IPR007641; RNA_pol_Rpb2_7.
 IPR014724; RNA_pol_RPB2_OB-fold.
 IPR019969; RNAP_B. 
Pfam
 PF04566; RNA_pol_Rpb2_4
 PF04567; RNA_pol_Rpb2_5
 PF00562; RNA_pol_Rpb2_6
 PF04560; RNA_pol_Rpb2_7 
SMART
  
PROSITE
 PS01166; RNA_POL_BETA 
PRINTS