CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023373
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translationally-controlled tumor protein homolog 
Protein Synonyms/Alias
 TCTP 
Gene Name
 Tctp 
Gene Synonyms/Alias
 CG4800 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
19EMFADTYKMKLVDDVacetylation[1]
21FADTYKMKLVDDVIYacetylation[1]
84CFAFGDKKSYTLYLKacetylation[1]
91KSYTLYLKDYMKKVLacetylation[1]
100YMKKVLAKLEEKSPDacetylation[1]
104VLAKLEEKSPDQVDIacetylation[1]
113PDQVDIFKTNMNKAMacetylation[1]
121TNMNKAMKDILGRFKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Involved in calcium binding and microtubule stabilization (By similarity). 
Sequence Annotation
 MOD_RES 50 50 Phosphoserine.
 MOD_RES 58 58 Phosphothreonine.
 MOD_RES 61 61 Phosphothreonine.  
Keyword
 Calcium; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 172 AA 
Protein Sequence
MKIYKDIITG DEMFADTYKM KLVDDVIYEV YGKLITRQGD DIKLEGANAS AEEADEGTDI 60
TSESGVDVVL NHRLTECFAF GDKKSYTLYL KDYMKKVLAK LEEKSPDQVD IFKTNMNKAM 120
KDILGRFKEL QFFTGESMDC DGMVALVEYR EINGDSVPVL MFFKHGLEEE KC 172 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; ISS:UniProtKB.
 GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:FlyBase.
 GO:0045793; P:positive regulation of cell size; IMP:FlyBase.
 GO:0040018; P:positive regulation of multicellular organism growth; IMP:FlyBase. 
Interpro
 IPR011057; Mss4-like.
 IPR011323; Mss4/transl-control_tumor.
 IPR018103; Translation_control_tumour_CS.
 IPR018105; Translational_control_tumour_p. 
Pfam
 PF00838; TCTP 
SMART
  
PROSITE
 PS01002; TCTP_1
 PS01003; TCTP_2 
PRINTS
 PR01653; TCTPROTEIN.