CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026508
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA1252 protein 
Protein Synonyms/Alias
  
Gene Name
 Sgpl1 
Gene Synonyms/Alias
 mKIAA1252 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
124VKNMPFLKVDKDYVKubiquitination[1]
148AEVLERLKEYSSMDGubiquitination[1]
370SISADTHKYGYAPKGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Lyase; Pyridoxal phosphate. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 585 AA 
Protein Sequence
GDAEAGQPRG GSRLQRKMPG TDLLKLKDFE PYLEILESYS TKAKNYVNGY CTKYEPWQLI 60
AWSVLCTLLI VWVYELIFQP ESLWSRFKKK LFKLIRKMPF IGRKIEQQVS KAKKDLVKNM 120
PFLKVDKDYV KTLPAQGMGT AEVLERLKEY SSMDGSWQEG KASGAVYNGE PKLTELLVQA 180
YGEFTWSNPL HPDIFPGLRK LEAEIVRMTC SLFNGGPDSC GCVTSGGTES ILMACKAYRD 240
LALEKGIKTP EIVAPESAHA AFDKAAHYFG MKIVRVALKK NMEVDVQAMK RAISRNTAML 300
VCSTPQFPHG VMDPVPEVAK LAVRYKIPLH VDACLGGFLI VFMEKAGYPL EKPFDFRVKG 360
VTSISADTHK YGYAPKGSSV VMYSNEKYRT YQFFVGADWQ GGVYASPSIA GSRPGGIIAA 420
CWAALMHFGE NGYVEATKQI IKTARFLKSE LENIKNIFIF GDPQLSVIAL GSNDFDIYRL 480
SNMMSAKGWN FNYLQFPRSI HFCITLVHTR KRVAIQFLKD IRESVTQIMK NPKAKTTGMG 540
AIYGMAQATI DRKLVAEISS VFLDCLYTTD PVTQGNQMNG SPKPR 585 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008209; P:androgen metabolic process; IMP:MGI.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
 GO:0006672; P:ceramide metabolic process; IEA:Compara.
 GO:0008210; P:estrogen metabolic process; IMP:MGI.
 GO:0060325; P:face morphogenesis; IMP:MGI.
 GO:0010761; P:fibroblast migration; IMP:MGI.
 GO:0030097; P:hemopoiesis; IMP:MGI.
 GO:0001822; P:kidney development; IMP:MGI.
 GO:0033327; P:Leydig cell differentiation; IMP:MGI.
 GO:0001553; P:luteinization; IMP:MGI.
 GO:0006807; P:nitrogen compound metabolic process; IMP:MGI.
 GO:0060021; P:palate development; IMP:MGI.
 GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.
 GO:0048705; P:skeletal system morphogenesis; IMP:MGI.
 GO:0007283; P:spermatogenesis; IMP:MGI.
 GO:0001570; P:vasculogenesis; IMP:MGI. 
Interpro
 IPR002129; PyrdxlP-dep_de-COase.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 
Pfam
 PF00282; Pyridoxal_deC 
SMART
  
PROSITE
  
PRINTS