CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033365
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Semaphorin-4D 
Protein Synonyms/Alias
  
Gene Name
 SEMA4D 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
81NALNISEKQHEVYWKubiquitination[1]
104CAEKGKSKQTECLNYubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 146 AA 
Protein Sequence
MRMCTPIRGL LMALAVMFGT AMAFAPIPRI TWEHREVHLV QFHEPDIYNY SALLLSEDKD 60
TLYIGAREAV FAVNALNISE KQHEVYWKVS EDKKAKCAEK GKSKQTECLN YIRVLQPLSA 120
TSLYVCGTNA FQPACDHLNL TSFKFL 146 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0010693; P:negative regulation of alkaline phosphatase activity; IEA:Compara.
 GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Compara.
 GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043931; P:ossification involved in bone maturation; IEA:Compara.
 GO:0050772; P:positive regulation of axonogenesis; IEA:Compara.
 GO:0030335; P:positive regulation of cell migration; IEA:Compara.
 GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Compara.
 GO:1900220; P:semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis; IEA:Compara. 
Interpro
 IPR027231; Semaphorin.
 IPR001627; Semaphorin/CD100_Ag.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
 PF01403; Sema 
SMART
  
PROSITE
 PS51004; SEMA 
PRINTS