CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018473
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Prostate tumor-overexpressed gene 1 protein homolog 
Protein Synonyms/Alias
  
Gene Name
 Ptov1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
176NRDCDSLKGLCRIMGubiquitination[1]
237RQVITTRKQAVGPGGubiquitination[1]
331LVQFHFTKDMETLKSubiquitination[1]
337TKDMETLKSLCRIMDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation (By similarity). 
Sequence Annotation
 REGION 184 416 Interaction with FLOT1 (By similarity).  
Keyword
 Activator; Cell membrane; Complete proteome; Cytoplasm; Membrane; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 416 AA 
Protein Sequence
MVRPRRAPHR SGAGGPLGGR GRPPRPLVVR AVRSRSWPGG PRGPQPPRIR ARSAPPMEGA 60
RVFGALGPIG PSSPGLTLGG LAVNEHRLSN KLLAWSGVLE WQEKRRPFSD STAKLKRTLP 120
CQAYVNQGEN LETDQWPQKL IMQLIPQQLL TTLGPLFRNS QLAQFHFTNR DCDSLKGLCR 180
IMGNGFAGCM LFPHISPCEV RVLMLLYSSK KKIFMGLIPY DQSGFVNAIR QVITTRKQAV 240
GPGGVHSGPV QIVNNKFLAW SGVMEWQEPR PEPNSRSKRW LPSHVYVNQG EILRTDQWPR 300
RLFMQLIPQQ LLTTLVPLFR NSRLVQFHFT KDMETLKSLC RIMDNGFAGC VHFSYKASCE 360
VRVLMLLYSS EKKIFIGLIP HDQSNFVNGI RRVIANQQQV LQRSLEQEQQ QRGMGG 416 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR021394; Mediator_Med25. 
Pfam
 PF11232; Med25 
SMART
  
PROSITE
  
PRINTS