CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L47, mitochondrial 
Protein Synonyms/Alias
 L47mt; MRP-L47; Nasopharyngeal carcinoma metastasis-related protein 1 
Gene Name
 MRPL47 
Gene Synonyms/Alias
 NCM1; CGI-204 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
144DSMDALDKVVQEREDacetylation[1, 2, 3, 4, 5]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 MOD_RES 144 144 N6-acetyllysine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Mitochondrion; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 250 AA 
Protein Sequence
MAAAGLALLC RRVSSALKSS RSLITPQVPA CTGFFLSLLP KSTPNVTSFH QYRLLHTTLS 60
RKGLEEFFDD PKNWGQEKVK SGAAWTCQQL RNKSNEDLHK LWYVLLKERN MLLTLEQEAK 120
RQRLPMPSPE RLDKVVDSMD ALDKVVQERE DALRLLQTGQ ERARPGAWRR DIFGRIIWHK 180
FKQWVIPWHL NKRYNRKRFF ALPYVDHFLR LEREKRARIK ARKENLERKK AKILLKKFPH 240
LAEAQKSSLV 250 
Gene Ontology
 GO:0005761; C:mitochondrial ribosome; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR010729; Ribosomal_L47_mit. 
Pfam
 PF06984; MRP-L47 
SMART
  
PROSITE
  
PRINTS