CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pantothenate kinase 
Protein Synonyms/Alias
 Pantothenic acid kinase; Rts protein 
Gene Name
 coaA 
Gene Synonyms/Alias
 panK; rts; b3974; JW3942 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
137LHPNQVLKERGLMKKacetylation[1]
158YDMHRLVKFVSDLKSacetylation[1]
264SYFHNYAKLTKEEAIacetylation[1]
267HNYAKLTKEEAIKTAacetylation[1]
279KTAMTLWKEINWLNLacetylation[1]
287EINWLNLKQNILPTRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 NP_BIND 95 102 ATP (Potential).  
Keyword
 3D-structure; ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 316 AA 
Protein Sequence
MSIKEQTLMT PYLQFDRNQW AALRDSVPMT LSEDEIARLK GINEDLSLEE VAEIYLPLSR 60
LLNFYISSNL RRQAVLEQFL GTNGQRIPYI ISIAGSVAVG KSTTARVLQA LLSRWPEHRR 120
VELITTDGFL HPNQVLKERG LMKKKGFPES YDMHRLVKFV SDLKSGVPNV TAPVYSHLIY 180
DVIPDGDKTV VQPDILILEG LNVLQSGMDY PHDPHHVFVS DFVDFSIYVD APEDLLQTWY 240
INRFLKFREG AFTDPDSYFH NYAKLTKEEA IKTAMTLWKE INWLNLKQNI LPTRERASLI 300
LTKSANHAVE EVRLRK 316 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IDA:EcoCyc.
 GO:0004594; F:pantothenate kinase activity; IDA:EcoCyc.
 GO:0015937; P:coenzyme A biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR004566; PanK_bact.
 IPR006083; PRK/URK. 
Pfam
 PF00485; PRK 
SMART
  
PROSITE
  
PRINTS