CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017572
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Late secretory pathway protein AVL9 homolog 
Protein Synonyms/Alias
  
Gene Name
 AVL9 
Gene Synonyms/Alias
 KIAA0241 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
465IHDPELRKLLNPTTAubiquitination[1, 2, 3]
608RNVVQTGKAVGQSVGubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Functions in cell migration. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Endosome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 648 AA 
Protein Sequence
MEKARRGGDG VPRGPVLHIV VVGFHHKKGC QVEFSYPPLI PGDGHDSHTL PEEWKYLPFL 60
ALPDGAHNYQ EDTVFFHLPP RNGNGATVFG ISCYRQIEAK ALKVRQADIT RETVQKSVCV 120
LSKLPLYGLL QAKLQLITHA YFEEKDFSQI SILKELYEHM NSSLGGASLE GSQVYLGLSP 180
RDLVLHFRHK VLILFKLILL EKKVLFYISP VNKLVGALMT VLSLFPGMIE HGLSDCSQYR 240
PRKSMSEDGG LQESNPCADD FVSASTADVS HTNLGTIRKV MAGNHGEDAA MKTEEPLFQV 300
EDSSKGQEPN DTNQYLKPPS RPSPDSSESD WETLDPSVLE DPNLKEREQL GSDQTNLFPK 360
DSVPSESLPI TVQPQANTGQ VVLIPGLISG LEEDQYGMPL AIFTKGYLCL PYMALQQHHL 420
LSDVTVRGFV AGATNILFRQ QKHLSDAIVE VEEALIQIHD PELRKLLNPT TADLRFADYL 480
VRHVTENRDD VFLDGTGWEG GDEWIRAQFA VYIHALLAAT LQLDNEKILS DYGTTFVTAW 540
KNTHNYRVWN SNKHPALAEI NPNHPFQGQY SVSDMKLRFS HSVQNSERGK KIGNVMVTTS 600
RNVVQTGKAV GQSVGGAFSS AKTAMSSWLS TFTTSTSQSL TEPPDEKP 648 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0055037; C:recycling endosome; IDA:UniProtKB.
 GO:0016477; P:cell migration; IDA:UniProtKB. 
Interpro
 IPR018307; Secretory_pathway_prot_Avl9. 
Pfam
 PF09794; Avl9 
SMART
  
PROSITE
  
PRINTS