UniProt Accession

 HN1_HUMAN; Q9UK76; B2R6K3; Q53FG7; Q7Z2D2; Q7Z2F0 

Genbank Protein ID

 AF086910; AY322169; AY322170; AF348672; AF348672; AF348672; AF177862; AF266846; AF266847; AK223321; AK312613; CH471099; BC001420; BC039343 

Genbank Nucleotide ID

 AAP97140.1; AAP83838.1; AAP83839.1; AAL83903.1; AAP83962.1; AAP83963.1; AAD53312.1; AAQ14298.1; AAQ14299.1; BAD97041.1; BAG35500.1; EAW89244.1; AAH01420.1; AAH39343.1 

Protein Name

 Hematological and neurological expressed 1 protein 

Protein Synonyms/Alias

 Androgen-regulated protein 2 

Gene Name

 HN1 

Gene Synonyms/Alias

 ARM2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
8	MTTTTTFKGVDPNSR	ubiquitination	[1, 2]
46	EQPVRKNKMASNIFG	ubiquitination	[2, 3]
64	ENQASWAKSAGAKSS	ubiquitination	[1, 2, 3]
69	WAKSAGAKSSGGRED	ubiquitination	[1, 2, 3]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

 MOD_RES 2 2 N-acetylthreonine.
 MOD_RES 49 49 Phosphoserine (By similarity).
 MOD_RES 54 54 Phosphothreonine.
 MOD_RES 61 61 Phosphoserine (By similarity).
 MOD_RES 80 80 Phosphoserine.
 MOD_RES 87 87 Phosphoserine.
 MOD_RES 88 88 Phosphoserine.
 MOD_RES 92 92 Phosphoserine (By similarity).
 MOD_RES 131 131 Phosphoserine.
 MOD_RES 148 148 N6-acetyllysine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 154 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS