| Tag | Content |
|---|
| CPLM ID | CPLM-015181 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative ATP-dependent RNA helicase DHX57 |
Protein Synonyms/Alias | DEAH box protein 57 |
Gene Name | Dhx57 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 32 | GGKGHMNKSHGGGGG | ubiquitination | [1] | | 396 | ISEFLYGKALEFAKT | ubiquitination | [1] | | 1239 | TPEGKFQKTSSGVVR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probable ATP-binding RNA helicase. |
Sequence Annotation | DOMAIN 175 220 UBA.
DOMAIN 555 722 Helicase ATP-binding.
DOMAIN 832 1012 Helicase C-terminal.
ZN_FING 299 326 C3H1-type.
NP_BIND 568 575 ATP (By similarity).
MOTIF 669 672 DEVH box.
MOD_RES 128 128 Phosphoserine (By similarity).
MOD_RES 475 475 Phosphoserine (By similarity). |
Keyword | Alternative splicing; ATP-binding; Coiled coil; Complete proteome; Helicase; Hydrolase; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1388 AA |
Protein Sequence | MSSSVRRKGK PGKGDGKGSS RGGRGGKGHM NKSHGGGGGG GGSCGGGGGG SRKASNRIWD 60
DGDDFCVFTE PKRPSRPCDS NKSKGETRPK WKPKAKVPLQ TLHMTSENQE KVKALLRDLQ 120
EQGADAGSER GTSGEEEDSE PQCGEEQGWP AGQEPIFLPD CSPWEYIGPE EVEPPVPECA 180
VSPLAVQKLS RYGFHTEHCQ LALRICDGDL GAALEHLLRQ CFSETFGERM ALSEAAVYVS 240
LNECVEQRQE ETLALKSICG EKFIERIQNR VWTIGLELDY LTNKFCKSKQ KESSKNVRDT 300
SPETCKFYLK GNCKFGSKCK FKHEVPPHQM IGRAERNVND PHLDADDDTT FMYELQIRFS 360
KDHKYPYQAP LVAFYSTNEN LPLACRLHIS EFLYGKALEF AKTSEPVVYS LITLLEEESE 420
IVKLLTHTQH KYSVPPVNVP PVPSETRISK PAYRKPVVPS NTFLSNQMLE GERLSELEED 480
ADEDEGPASI IVENESYVNL KKRSYKRYDR PAKSLFAENS KICRQFQMKQ ASRQFHAILQ 540
ERQLLPAWEE RETILKLLSK HQVVVISGMT GCGKTTQIPQ FILDNSLNGP PERVANIICT 600
QPRRISAISV AERVAKERAE RVGLTVGYQI RLESVKSSAT RLLYCTTGVL LRRLEGDATL 660
QGVTHIIVDE VHERTEESDF LLLVLKDIVM QRATLQVILM SATLDAGLFS KYFSYCPVIT 720
IPGRAFPVDQ FFLEDALAVT RYVLQDGSPY MRSMKQIAKE KLKARHNRTA QEEVEEDLRL 780
SLHLQDEEES VKDTIPDQQL DFKQLLIRYK GVSKSVIKTM SVMDFEKVNL ELIEALLEWI 840
VDGKHAYPPG AVLVFLPGLA EIKMLYEQLQ SNSLFNNRRS HRCVIHPLHS SLSSEEQQAV 900
FVKPPMGVTK IIISTNIAET SITIDDVVYV IDSGKMKEKR YDAGKGMESL EDTFVSQANA 960
LQRKGRAGRV ASGVCFHLFT SHHYNHQLLK QQLPEIQRVP LEQLCLRIKI LEMFSTHNLQ 1020
SVFSRLIEPP HIDSLRASKV RLRDLGALTP DEKLTPLGYH LASLPVDVRI GKLMLLGSIF 1080
RCLDPALTIA ASLAFKSPFV SPWDKKEEAN QKKLEFAFAN SDYLALLCAY KGWQLSTKES 1140
ARASYNYCRQ NFLSGRTLQE MASLKRQFTE LLSDIGFVKE GLRAKEIEKR AQGGDGVLDA 1200
TGEEANTNAE NPKLISAVLC AALYPNVVQV KTPEGKFQKT SSGVVRLQPK SAELKFVTKN 1260
DGYVHIHPSS VNYQVRHFDS PYLLYHEKIK TSRVFIRDCS MVSVYPLVLF GGGQVNVQLQ 1320
RGAFVVSLDD GWIRFVAASH QVAELVKELR CELDQLLQDK IKNPSMDLCS CPRGSRIISM 1380
IVKLITTQ 1388 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |