| Tag | Content |
|---|
| CPLM ID | CPLM-013727 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ferrochelatase |
Protein Synonyms/Alias | Heme synthase; Protoheme ferro-lyase |
Gene Name | hemH |
Gene Synonyms/Alias | GK0662 |
Created Date | July 27, 2013 |
Organism | Geobacillus kaustophilus (strain HTA426) |
NCBI Taxa ID | 235909 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 34 | THIRHGRKPPQEQIE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus. Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG. Proteomics. 2013 Aug;13(15):2278-82. [ PMID: 23696451] |
Functional Description | Catalyzes the ferrous insertion into protoporphyrin IX (By similarity). |
Sequence Annotation | METAL 183 183 Iron (By similarity).
METAL 264 264 Iron (By similarity). |
Keyword | Complete proteome; Cytoplasm; Heme biosynthesis; Iron; Lyase; Metal-binding; Porphyrin biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 316 AA |
Protein Sequence | MVKKTAGLLV MAYGTPYRED DIERYYTHIR HGRKPPQEQI EDLKARYRAI GGLSPLAKIT 60
EEQAKRLEER LNEVQDEVEF RMYLGLKHIE PFIEDAVERM HDDGIKEAVG IVLAPHYSTF 120
SIRSYNERAK AAAKKLGGPT IYTIDQWYDE PKFLQYWAEQ VRAIFAAMPE RERERAVLIV 180
SAHSLPEKII QAGDPYPTQL EDTAKRIADQ AGVAHYAVGW QSAGQTPEPW LGPDVQDLTR 240
QLYEERGYTS FVYAPVGFVA DHLEVLYDND IECKQVTEEI GARYYRPEMP NTNPLFIDAL 300
ASVVLKRWAE EGDRHE 316 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004325; F:ferrochelatase activity; IEA:HAMAP. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006783; P:heme biosynthetic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |