CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007122
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lysophospholipid transporter LplT 
Protein Synonyms/Alias
  
Gene Name
 lplT 
Gene Synonyms/Alias
 ygeD; b2835; JW2803 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
132GELTTGSKLVKANGLacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell. 
Sequence Annotation
  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Lipid transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 397 AA 
Protein Sequence
MSESVHTNTS LWSKGMKAVI VAQFLSAFGD NALLFATLAL LKAQFYPEWS QPILQMVFVG 60
AYILFAPFVG QVADSFAKGR VMMFANGLKL LGAASICFGI NPFLGYTLVG VGAAAYSPAK 120
YGILGELTTG SKLVKANGLM EASTIAAILL GSVAGGVLAD WHVLVALAAC ALAYGGAVVA 180
NIYIPKLAAA RPGQSWNLIN MTRSFLNACT SLWRNGETRF SLVGTSLFWG AGVTLRFLLV 240
LWVPVALGIT DNATPTYLNA MVAIGIVVGA GAAAKLVTLE TVSRCMPAGI LIGVVVLIFS 300
LQHELLPAYA LLMLIGVMGG FFVVPLNALL QERGKKSVGA GNAIAVQNLG ENSAMLLMLG 360
IYSLAVMIGI PVVPIGIGFG ALFALAITAL WIWQRRH 397 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:EcoCyc.
 GO:0051978; F:lysophospholipid transporter activity; IMP:EcoCyc.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR023727; LysoPLipid__transptr_LplT.
 IPR011701; MFS.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS