| Tag | Content |
|---|
| CPLM ID | CPLM-002936 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA-binding protein fis |
Protein Synonyms/Alias | Factor-for-inversion stimulation protein; Hin recombinational enhancer-binding protein |
Gene Name | fis |
Gene Synonyms/Alias | b3261; JW3229 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 25 | SQDQVTQKPLRDSVK | acetylation | [1] | | 32 | KPLRDSVKQALKNYF | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC. |
Sequence Annotation | DNA_BIND 74 93 H-T-H motif.
REGION 17 44 Required for the stimulation of HIN- |
Keyword | 3D-structure; Activator; Complete proteome; Direct protein sequencing; DNA-binding; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 98 AA |
Protein Sequence | MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ 60
PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN 98 |
Gene Ontology | GO:0000787; C:cytoplasmic nucleosome; IDA:EcoCyc. GO:0043565; F:sequence-specific DNA binding; IDA:EcoliWiki. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:HAMAP. GO:0034401; P:regulation of transcription by chromatin organization; IDA:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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