CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013639
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 59-like 
Protein Synonyms/Alias
 Brain-specific membrane-anchored protein 
Gene Name
 Tmem59l 
Gene Synonyms/Alias
 Bsmap 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
325SPPPYKLKLDLTTL*ubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (By similarity). 
Sequence Annotation
 MOTIF 329 331 Microbody targeting signal (Potential).
 CARBOHYD 90 90 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 331 AA 
Protein Sequence
MAAVALPLLL LLASPATPTP ARDPFSPQLG DTQRCQQRCR QRHPGLPPAQ PEPEGPSESP 60
NNKAVLINAC ERGCRLFSIC RFVARSSRPN ATETECEAAC TEAYVKAKEQ QACSEGCWGQ 120
IPEPETQLEQ KELALDPPSG SLSLRHLFTM LCSDLMSSAQ DLISSTWTYS LQTDNRKTQP 180
VVENFAFQGS RLQRVEVTWR GSHPKALEVH MDPMSPLEKV RRAKPHLKTS KAKVESEDQQ 240
ESDFLSCMSR RSGLPRWVLF CCLFLSVLII LWLSCCTLVT TPGQHLKFQP LTAEQHKGLL 300
VESNWPLYPP LPPAYEDSPP PYKLKLDLTT L 331 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR022065; Uncharacterised_TMEM59. 
Pfam
 PF12280; BSMAP 
SMART
  
PROSITE
  
PRINTS