Tag | Content |
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CPLM ID | CPLM-013639 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane protein 59-like |
Protein Synonyms/Alias | Brain-specific membrane-anchored protein |
Gene Name | Tmem59l |
Gene Synonyms/Alias | Bsmap |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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325 | SPPPYKLKLDLTTL* | ubiquitination | [1] |
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Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (By similarity). |
Sequence Annotation | MOTIF 329 331 Microbody targeting signal (Potential). CARBOHYD 90 90 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 331 AA |
Protein Sequence | MAAVALPLLL LLASPATPTP ARDPFSPQLG DTQRCQQRCR QRHPGLPPAQ PEPEGPSESP 60 NNKAVLINAC ERGCRLFSIC RFVARSSRPN ATETECEAAC TEAYVKAKEQ QACSEGCWGQ 120 IPEPETQLEQ KELALDPPSG SLSLRHLFTM LCSDLMSSAQ DLISSTWTYS LQTDNRKTQP 180 VVENFAFQGS RLQRVEVTWR GSHPKALEVH MDPMSPLEKV RRAKPHLKTS KAKVESEDQQ 240 ESDFLSCMSR RSGLPRWVLF CCLFLSVLII LWLSCCTLVT TPGQHLKFQP LTAEQHKGLL 300 VESNWPLYPP LPPAYEDSPP PYKLKLDLTT L 331 |
Gene Ontology | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. |
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