CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028511
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Chd5 
Protein Synonyms/Alias
  
Gene Name
 Chd5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1870EELLSDMKADVTRLPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1946 AA 
Protein Sequence
MRGPLGTEEE LPRLFAEEME NEEEMSEEED GGLEGFEDFF PAEPVSLPKK KPKKLKESKS 60
SKGKRKKKEG SNDEMSDNEE DLEEKSESEG SDYSPTKKKK KKLKEKKEKK EKKEKRKKRG 120
EDEDDNDDGG LKEPKSSGQL MAEWGLDDVD YLFSEDDYHT LTNYKAFSQF LRPLIAKKNP 180
KIPMSKMMTV LGAKWREFSA NNPFKGSSAA AAAAAVAAAV ETVTIAPPLA ISPQQVPQTL 240
PIRKAKTKEG KGPGVRKKNK GAKDSKKKGR GKRVAGLKFR FGGISKRKKG SSSEEDERED 300
SDLDNASIHS SSVRSECSAA LGKKNKRRRK KKRIDDGDGY ETDHQDYCEV CQQGGEIILC 360
DTCPRAYHLV CLDPELEKAP EGKWSCPHCE KEGIQWEPKD DDEEEEEGGC EEEEDDHMEF 420
CRVCKDGGEL LCCDACPSSY HLHCLNPPLP EIPNGEWLCP RCTCPPLKGK VQRILHWRWT 480
EPPAPFVVGL PGPEVEPGMP PPRPLEGIPE REFFVKWAGL SYWHCSWVKE LQLELYHTVM 540
YRNYQRKNDM DEPPPFDYGS GDEDGKSEKR KNKDPLYAKM EERFYRYGIK PEWMMVHRIL 600
NHSFDKKGDI HYLIKWKDLP YDQCTWEIDE IDIPYYDNLK QAYWGHRELM LGEDARLPKR 660
LVKKGKKLKD DKQEKPPDTP IVDPTVKFDK QPWYIDATGG TLHPYQLEGL NWLRFSWAQG 720
TDTILADEMG LGKTVQTIVF LYSLYKEGHS KGPYLVSAPL STIINWEREF EMWAPDFYVV 780
TYTGDKESRS VIRENEFSFE DNAIRGGKKV FRMKKEVQIK FHVLLTSYEL ITIDQAILGS 840
IEWACLVVDE AHRLKNNQSK FFRVLNSYKI DYKLLLTGTP LQNNLEELFH LLNFLTPERF 900
NNLEGFLEEF ADISKEDQIK KLHDLLGPHM LRRLKADVFK NMPAKTELIV RVELSQMQKK 960
YYKFILTRNF EALNSKGGGN QVSLLNIMMD LKKCCNHPYL FPVAAVEAPV LPNGSYDGSS 1020
LVKSSGKLML LQKMLKKLRD EGHRVLIFSQ MTKMLDLLED FLEYEGYKYE RIDGGITGGL 1080
RQEAIDRFNA PGAQQFCFLL STRAGGLGIN LATADTVIIY DSDWNPHNDI QAFSRAHRIG 1140
QNKKVMIYRF VTRASVEERI TQVAKRKMML THLVVRPGLG SKSGSMTKQE LDDILKFGTE 1200
ELFKDDVEGM MSQGQRPTTP IPDIQSTKGG SLTAGAKKKH GSTPPGDNKD VEDSSVIHYD 1260
DAAISKLLDR NQDATDDTEL QNMNEYLSSF KVAQYVVREE DGVEEVEREV IKQEENVDPD 1320
YWEKLLRHHY EQQQEDLARN LGKGKRIRKQ VNYNDASQED QEWQDELSDN QSEYSIGSED 1380
EDEDFEERPE GQSGRRQSRR QLKSDRDKPL PPLLARVGGN IEVLGFNARQ RKAFLNAIMR 1440
WGMPPQDAFN SHWLVRDLRG KSEKEFRAYV SLFMRHLCEP GADGAETFAD GVPREGLSRQ 1500
HVLTRIGVMS LVRKKVQEFE HVNGKYSTPD LVPEGAEGKK PGEVISSDPN TPVPASPAQL 1560
PPAPLGLTDK MEAQLGYTDE KESGMQKPKK SLEIQTLPTA LDRVEGEDKH QSSDSKDRAR 1620
EERTEEVEKA QGSPEQPLKE EVLPDKEPIP DKPELSLGHS GDFRPDDPKT EEKEPGETQQ 1680
NGDREEDEEG KKEDKNGKFK FMFNIADGGF TELHTLWQNE ERAAVSSGKI YEIWHRRHDY 1740
WLLAGIVTHG YARWQDIQND PRYMILNEPF KSEIHKGNYL EMKNKFLARR FKLLEQALVI 1800
EEQLRRAAYL NMTQDPNHPA MALNARLAEV ECLAESHQHL SKESLAGNKP ANAVLHKVLN 1860
QLEELLSDMK ADVTRLPSML SRIPPVAARL QMSERSILSR LTNRAGDPTI QQTSSRRRDF 1920
PLFQRSFPAE PSHLPNPRGR EKLQPF 1946 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR012957; CHD_C2.
 IPR012958; CHD_N.
 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR002464; DNA/RNA_helicase_DEAH_CS.
 IPR009462; DUF1086.
 IPR009463; DUF1087.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000330; SNF2_N.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF08074; CHDCT2
 PF08073; CHDNT
 PF00385; Chromo
 PF06461; DUF1086
 PF06465; DUF1087
 PF00271; Helicase_C
 PF00628; PHD
 PF00176; SNF2_N 
SMART
 SM00298; CHROMO
 SM00487; DEXDc
 SM00490; HELICc
 SM00249; PHD
 SM00184; RING 
PROSITE
 PS50013; CHROMO_2
 PS00690; DEAH_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS