| Tag | Content |
|---|
| CPLM ID | CPLM-005776 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanine nucleotide-binding protein subunit beta-4 |
Protein Synonyms/Alias | Transducin beta chain 4 |
Gene Name | Gnb4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 23 | NQIQDARKACNDATL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Sequence Annotation | REPEAT 53 92 WD 1.
REPEAT 95 134 WD 2.
REPEAT 141 179 WD 3.
REPEAT 182 221 WD 4.
REPEAT 224 263 WD 5.
REPEAT 268 307 WD 6.
REPEAT 310 339 WD 7.
MOD_RES 2 2 N-acetylserine (By similarity). |
Keyword | Acetylation; Complete proteome; Reference proteome; Repeat; Transducer; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 340 AA |
Protein Sequence | MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120
CSIYNLKTRE GNVRVSRELP GHTGYLSCCR FLDDGQIITS SGDTTCALWD IETGQQTTTF 180
TGHSGDVMSL SLSPDLKTFV SGACDASSKL WDIRDGMCRQ SFTGHISDIN AVSFFPSGYA 240
FATGSDDATC RLFDLRADQE LLLYSHDNII CGITSVAFSK SGRLLLAGYD DFNCSVWDAL 300
KGGRSGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLRIWN 340 |
Gene Ontology | GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI. GO:0003924; F:GTPase activity; ISA:MGI. GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |