CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041803
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lysosomal protective protein 
Protein Synonyms/Alias
 Protective protein for beta-galactosidase, isoform CRA_b 
Gene Name
 Ctsa 
Gene Synonyms/Alias
 Ppgb; mCG_17533 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
360LNNPYVRKALHIPESacetylation[1]
395SMNSQYLKLLSSQKYacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MTSSPKAPPG EQGRKEAEMP GTALSPLLLL LLLSWASRNE AAPDQDEIDC LPGLAKQPSF 60
RQYSGYLRAS DSKHFHYWFV ESQNDPKNSP VVLWLNGGPG CSSLDGLLTE HGPFLIQPDG 120
VTLEYNPYAW NLIANVLYIE SPAGVGFSYS DDKMYVTNDT EVAENNYEAL KDFFRLFPEY 180
KDNKLFLTGE SYAGIYIPTL AVLVMQDPSM NLQGLAVGNG LASYEQNDNS LVYFAYYHGL 240
LGNRLWTSLQ THCCAQNKCN FYDNKDPECV NNLLEVSRIV GKSGLNIYNL YAPCAGGVPG 300
RHRYEDTLVV QDFGNIFTRL PLKRRFPEAL MRSGDKVRLD PPCTNTTAPS NYLNNPYVRK 360
ALHIPESLPR WDMCNFLVNL QYRRLYQSMN SQYLKLLSSQ KYQILLYNGD VDMACNFMGD 420
EWFVDSLNQK MEVQRRPWLV DYGESGEQVA GFVKECSHIT FLTIKGAGHM VPTDKPRAAF 480
TMFSRFLNKE PY 492 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR001563; Peptidase_S10.
 IPR018202; Peptidase_S10_AS. 
Pfam
 PF00450; Peptidase_S10 
SMART
  
PROSITE
 PS00560; CARBOXYPEPT_SER_HIS
 PS00131; CARBOXYPEPT_SER_SER 
PRINTS
 PR00724; CRBOXYPTASEC.