CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026513
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0248 protein 
Protein Synonyms/Alias
 Prostaglandin E synthase 2 
Gene Name
 Gbf1 
Gene Synonyms/Alias
 mKIAA0248 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
551NTLNQQEKKETARPGubiquitination[1]
899LEETIIQKAISGFRKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1803 AA 
Protein Sequence
ELSEIEPNVF LRPFLEVIRS EDTTGPITGL ALTSVNKFLS YALIDPTHEG TAEGMENMAD 60
AVTHARFVGT DPASDEVVLM KILQVLRTLL LTPVGTHLTN ESVCEIMQSC FRICFEMRLS 120
ELLRKSAEHT LVDMVQLLFT RLPQFKEEPK SYVGTNMKKL KMRAGGMSDS SKWKKQKRSP 180
RPPRHTTKVT PGSELPTPNG ATLPSNLTGG VPFIDAPTSI SSASSEAAST VVSPCTDSGL 240
ELSSQTTSKE DLTDLEQAGS PREITTSEPG SSEMGASDQL DPQEGAHVEK AQSASVESIP 300
EVLEECTSPA DHSDSASVHD MDYVNPRGVR FTQSSQKEGT ALVPYGLPCI RELFRFLISL 360
TNPHDRHNSE VMIHMGLHLL TVALESAPVA QCQTLLGLIK DEMCRHLFQL LSVERLNLYA 420
ASLRVCFLLF ESMREHLKFQ LEMYIKKLME IITVENPKMP YEMKEMALEA VVQLWRIPSF 480
VTELYINYDC DYYCSNLFED LTKLLSKNAF PVSGQLYTTH LLSLDALLTV IDSTESHCQA 540
KVLNTLNQQE KKETARPGFE AVDGNPETNK SERATSDGKS TGVALDARGL HFPSGGWLST 600
EHGKPGCRDL EEAGDSGADK KFTRKPPRFS CLLPDPRELI EIKNKKKLLI TGTEQFNQKP 660
KKGIQFLQEK GLLTIPMDNT EVAQWLRENP RLDKKMIGEF VSDRKNMDLL ESFVSTFSFQ 720
GLRLDEALRL YLEAFRLPGE APVIHRLLEV FTEHWRSCNG SPFANSDACF ALAYAVIMLN 780
TDQHNHNVRK QNAPMTLEEF RKNLKGVNGG KDFEQDILED MYHAIKNEEI VMPEEQTGLV 840
RENYVWSVLL HRGASPEGVF LRVPPGSYDL DLFTMTWGPT IAALSYVFDK SLEETIIQKA 900
ISGFRKCAMI SAHYGLSDVF DNLIISLCKF TALSSESIEN LPSVFGSNPK AHIAAKTVFH 960
LAHRHGDILR EGWKNIMEAM LQLFRAQLLP KAMVEVEDFV DPNGKISLQR EETPSNRGES 1020
TVLSFVSWLT LSGPEQSSVR GPSTENQEAK RVALDCIKQC DPEKMITESK FLQLESLQEL 1080
MKALVSVTPD EETYDEEDAA FCLEMLLRIV LENRDRVGCV WQTVRDHLYH LCVQAQDFCF 1140
LVERAVVGLL RLAIRLLRRE EISGQVLLSL RILLLMKPSV LSRVSHQVAY GLHELLKTNA 1200
ANIHSGDDWA TLFTLLECIG SGVKPPDALQ ATARADAPDA GAQSDSELPS YHQNDVSLDR 1260
GYTSDSEVYT DHGRPGKIHR SATDADMVNS GWLVVGKDDI DNSKPGAGLS RPGPSPLVNQ 1320
YSLTVGLDLG PHDTKSLLKC VESLSFIVRD AAHITPDNFE LCVKTLRIFV EASLNGGCKS 1380
QDKRSKSHKY DSKGNRFKKK PKEGSMLRRP RGSNQHATRG GHSDEEEDEG VPASYHTVSL 1440
QLLDLMHTLH TRAASIYSSW AEEQRHLEGG GQKIEADSRT LWAHCWCPLL QGIACLCCDA 1500
RRQVRMQALT YLQRALLVHD LQKLDALEWE SCFNKVLFPL LTKLLENISP ADVGGMEETR 1560
MRASTLLSKV FLQHLSPLLS LSTFAALWLT ILDFMDKYMH AGSSDLLSEA IPESLKNMLL 1620
VMDTAEIFHS ADARGGGPSA LWEITWERID CFLPHLRDEL FKQTVIQDPM PAEPHSQKPL 1680
ASTHLTSAAG DPRMPGHPPL PEIPSEMGVC DSEKPESTRA PSSSSPGSPM ASSPSKLSPA 1740
QEGPPPLTQP PLILQPLTSP LQVGVPPMTL PIILNPALIE ATSPVPLLAT PRPTDPIPTS 1800
EVN 1803 
Gene Ontology
 GO:0005802; C:trans-Golgi network; IBA:RefGenome.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IBA:RefGenome. 
Interpro
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 
Pfam
 PF01369; Sec7 
SMART
 SM00222; Sec7 
PROSITE
 PS50190; SEC7 
PRINTS