CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024409
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cellulose synthase A catalytic subunit 4 [UDP-forming] 
Protein Synonyms/Alias
 OsCesA4 
Gene Name
 CESA4 
Gene Synonyms/Alias
 OsI_03742 
Created Date
 July 27, 2013 
Organism
 Oryza sativa subsp. indica (Rice) 
NCBI Taxa ID
 39946 
Lysine Modification
Position
Peptide
Type
References
755GYGGGRLKWLQRLSYubiquitination[1]
Reference
 [1] Proteomic analysis of salt-responsive ubiquitin-related proteins in rice roots.
 Liu CW, Hsu YK, Cheng YH, Yen HC, Wu YP, Wang CS, Lai CC.
 Rapid Commun Mass Spectrom. 2012 Aug 15;26(15):1649-60. [PMID: 22730086
Functional Description
 Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation (By similarity). Involved in the secondary cell wall formation. 
Sequence Annotation
 ZN_FING 9 47 RING-type; degenerate.
 ACT_SITE 308 308 Potential.
 ACT_SITE 688 688 Potential.
 METAL 9 9 Zinc 1 (By similarity).
 METAL 12 12 Zinc 1 (By similarity).
 METAL 20 20 Zinc 2 (By similarity).
 METAL 23 23 Zinc 2 (By similarity).
 METAL 28 28 Zinc 1 (By similarity).
 METAL 31 31 Zinc 1 (By similarity).
 METAL 43 43 Zinc 2 (By similarity).
 METAL 46 46 Zinc 2 (By similarity).
 BINDING 474 474 Substrate (Potential).
 BINDING 476 476 Substrate (Potential).
 CARBOHYD 862 862 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Cell wall biogenesis/degradation; Cellulose biosynthesis; Coiled coil; Glycoprotein; Glycosyltransferase; Membrane; Metal-binding; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 989 AA 
Protein Sequence
MMESGVPPCA ACGDDAHAAC RACSYALCKA CLDEDAAEGR TTCARCGGEY GAPDPAHGQG 60
AVVEEEVEES HEPVASGVRE RVTMASQLSD HQDEGVHART MSTHARTISS VSGVGSELND 120
ESGKPIWKNR VESWKEKKKE KKASAKKAAA KAQAPPVEEQ IMDEKDLTDA YEPLSRIIPI 180
SKNKLTPYRA VIIMRLVVLG LFFHYRITNP VYSAFGLWMT SVICEIWFGF SWILDQFPKW 240
CPINRETYVD RLIARYGDGE DSGLAPVDFF VSTVDPLKEP PLITANTVLS ILAVDYPVEK 300
ISCYVSDDGS AMLTFESLAE TAEFARRWVP FCKKYSIEPR APEFYFSQKI DYLKDKIHPS 360
FVKERRAMKR DYEEYKVRIN ALVAKAQKTP EEGWIMQDGT PWPGNNPRDH PGMIQVFLGE 420
TGARDFDGNE LPRLVYVSRE KRPGYQHHKK AGAMNALVRV SAVLTNAPYI LNLDCDHYVN 480
NSKAVREAMC FMMDPSVGRD VCYVQFPQRF DGIDRSDRYA NRNVVFFDVN MKGLDGLQGP 540
VYVGTGCCFY RQALYGYGPP SLPALPKSSV CSWCCCCCPK KKAEKSEKEM HRDSRREDLE 600
SAIFNLREID NYDEYERSML ISQMSFEKSF GLSSVFIEST LMENGGVPES ANPSTLIKEA 660
IHVISCGYEE KTEWGKEIGW IYGSVTEDIL TGFKMHCRGW RSIYCMPIRP AFKGSAPINL 720
SDRLHQVLRW ALGSVEIFLS RHCPLWYGYG GGRLKWLQRL SYINTIVYPF TSLPLIAYCC 780
LPAICLLTGK FIIPTLSNAA TIWFLGLFIS IIVTSVLELR WSGIGIEDWW RNEQFWVIGG 840
VSAHLFAVFQ GILKMIAGLD TNFTVTAKAT DDTEFGELYV FKWTTVLIPP TSILVLNLVG 900
VVAGFSDALN SGYESWGPLF GKVFFAMWVI MHLYPFLKGL MGRQNRTPTI VVLWSVLLAS 960
VFSLLWVKID PFIGSSETTT TNSCANFDC 989 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR005150; Cellulose_synth.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF03552; Cellulose_synt 
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS