| Tag | Content |
|---|
| CPLM ID | CPLM-002398 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SPT2 |
Protein Synonyms/Alias | Negative regulator of Ty transcription |
Gene Name | SPT2 |
Gene Synonyms/Alias | SIN1; SPM2; YER161C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 6 | **MSFLSKLSQIRKS | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Chromatin protein. Global regulatory protein that plays positive as well as negative regulatory roles in transcription. |
Sequence Annotation | MOD_RES 126 126 Phosphoserine. |
Keyword | Activator; Coiled coil; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 333 AA |
Protein Sequence | MSFLSKLSQI RKSTTASKAQ VQDPLPKKND EEYSLLPKNY IRDEDPAVKR LKELRRQELL 60
KNGALAKKSG VKRKRGTSSG SEKKKIERND DDEGGLGIRF KRSIGASHAP LKPVVRKKPE 120
PIKKMSFEEL MKQAENNEKQ PPKVKSSEPV TKERPHFNKP GFKSSKRPQK KASPGATLRG 180
VSSGGNSIKS SDSPKPVKLN LPTNGFAQPN RRLKEKLESR KQKSRYQDDY DEEDNDMDDF 240
IEDDEDEGYH SKSKHSNGPG YDRDEIWAMF NRGKKRSEYD YDELEDDDME ANEMEILEEE 300
EMARKMARLE DKREEAWLKK HEEEKRRRKK GIR 333 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0000217; F:DNA secondary structure binding; IDA:SGD. GO:0006325; P:chromatin organization; IMP:SGD. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD. GO:0043631; P:RNA polyadenylation; IMP:SGD. GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |