| Tag | Content |
|---|
| CPLM ID | CPLM-024244 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Catalase-peroxidase 2 |
Protein Synonyms/Alias | CP 2; Peroxidase/catalase 2 |
Gene Name | katG2 |
Gene Synonyms/Alias | katH; MSMEG_3461; MSMEI_3380 |
Created Date | July 27, 2013 |
Organism | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) |
NCBI Taxa ID | 246196 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 149 | PDNVSLDKARRLLWP | pupylation | [1] |
|
Reference | [1] Proteome-wide identification of mycobacterial pupylation targets. Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH. Mol Syst Biol. 2010 Jul 13;6:386. [ PMID: 20631680] |
Functional Description | Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity. May play a role in the intracellular survival of mycobacteria. |
Sequence Annotation | ACT_SITE 114 114 Proton acceptor (By similarity).
METAL 279 279 Iron (heme axial ligand) (By similarity).
CROSSLNK 113 238 Tryptophyl-tyrosyl-methioninium (Trp-Tyr)
CROSSLNK 238 264 Tryptophyl-tyrosyl-methioninium (Tyr-Met) |
Keyword | Complete proteome; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 748 AA |
Protein Sequence | MSSDTSDSRP PNPDTKTAST SESENPAIPS PKPKSGAPLR NQDWWPNQID VSRLHPHPPQ 60
GNPLGEDFDY AEEFAKLDVN ALKADLTALM TQSQDWWPAD YGHYGGLFIR MSWHSAGTYR 120
IHDGRGGGGQ GAQRFAPINS WPDNVSLDKA RRLLWPIKQK YGNKISWADL LVFTGNVALE 180
SMGFKTFGFG FGREDIWEPE EILFGEEDEW LGTDKRYGGG EQRQLAEPYG ATTMGLIYVN 240
PEGPEGQPDP LAAAHDIRET FGRMAMNDEE TAALIVGGHT FGKTHGAGDA SLVGPEPEAA 300
PIEQQGLGWK SSYGTGKGPD TITSGLEVVW TNTPTKWDNS FLEILYGYEW ELTKSPAGAW 360
QFTAKDGAGA GTIPDPFGGP GRNPTMLVTD ISMRVDPIYG KITRRWLDHP EELSEAFAKA 420
WYKLLHRDMG PISRYLGPWV AEPQLWQDPV PAVDHPLVDD QDIAALKSTV LDSGLSTGQL 480
IKTAWASAAS YRNTDKRGGA NGARVRLEPQ KNWDVNEPAE LATVLPVLER IQQDFNASAS 540
GGKKVSLADL IVLAGSAAIE KAAKDGGYNV TVPFAPGRTD ASQENTDVES FAVLEPRADG 600
FRNYVRPGEK VQLEKMLLER AYFLGVTAPQ LTALVGGLRA LDVNHGGTKH GVFTDRPGAL 660
TNDFFVNLLD MGTEWKTSET TENVYEGVDR KTGQLKWTAT ANDLVFGSHS VLRAVAEVYA 720
QSDNGERFVN DFVKAWVKVM NNDRFDLK 748 |
Gene Ontology | GO:0004096; F:catalase activity; IEA:HAMAP. GO:0020037; F:heme binding; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |