CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017542
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 610 
Protein Synonyms/Alias
  
Gene Name
 ZNF610 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
412CDKVFGRKLYLTNHQubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 24 95 KRAB.
 ZN_FING 204 226 C2H2-type 1; degenerate.
 ZN_FING 232 254 C2H2-type 2.
 ZN_FING 260 282 C2H2-type 3.
 ZN_FING 288 310 C2H2-type 4.
 ZN_FING 316 338 C2H2-type 5.
 ZN_FING 344 366 C2H2-type 6.
 ZN_FING 372 394 C2H2-type 7.
 ZN_FING 400 422 C2H2-type 8.
 ZN_FING 428 450 C2H2-type 9.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MLCDEEAQKR KAKESGMALP QGRLTFMDVA IEFSQEEWKS LDPGQRALYR DVMLENYRNL 60
VFLGICLPDL SIISMLKQRR EPLILQSQVK IVKNTDGREC VRSVNTGRSC VLGSNAENKP 120
IKNQLGLTLE AHLSELQLFQ AGRKIYRSNQ VEKFTNHRSS VSPLQKISSS FTTHIFNKYR 180
NDLIDFPLLP QEEKAYIRGK SYEYECSEDG EVFRVRASLT NHQVIHTAEK PYKCTECGKV 240
FSRNSHLVEH WRIHTGQKPY KCSECDKVFN RNSNLARHQR IHTGEKPHKC NECGKAFREC 300
SGLTTHLVIH TGEKPYKCNE CGKNFRHKFS LTNHQRSHTA EKPYKCNECG KVFSLLSYLA 360
RHQIIHSTEK PYKCNECGRA FHKRPGLMAH LLIHTGEKPY KCNECDKVFG RKLYLTNHQR 420
IHTGERPYKC NACGKVFNQN PHLSRHRKIH AGENSLRTLQ ME 462 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS