CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042283
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Flnc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
735RCSYVPTKPIKHTIIacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2726 AA 
Protein Sequence
MMNNSGYPDA SGFGLGDEAD EMPSTEKDLA EDAPWKKIQQ NTFTRWCNEH LKCVGKRLTD 60
LQRDLSDGLR LIALLEVLSQ KRMYRKFHPR PNFRQMKLEN VSVALEFLER EHIKLVSIDS 120
KAIVDGNLKL ILGLIWTLIL HYSISMPMWE DEDDEDARKQ TPKQRLLGWI QNKVPQLPIT 180
NFNRDWQDGK ALGALVDNCA PGLCPDWEAW DPNQPVQNAR EAMQQADDWL GVPQVIAPEE 240
IVDPNVDEHS VMTYLSQFPK AKLKPGAPVR SKQLNPKKAI AYGPGIEPHG NTVLQPAHFT 300
VQTVDAGLGE VLVYIEDPEG HTEEAKVVPN NDKDRTYAVS YVPKVAGLHK VTVLFAGQNI 360
ERSPFEVNVG MALGDANKVS ARGPGLEPVG NVANKPTYFD IYTAGAGTGD VAVVIVDPQG 420
RQDTVEVALE DKGDSTFRCT YRPVMEGPHT VHVAFAGSPI TRSPFPVHVA EACNPNACRA 480
SGRGLQPKGV RVKEVADFKV FTKGAGSGEL KVTVKGPKGT EELVKVREAG DGVFECEYYP 540
VVPGKYVVTI TWGGYAIPRS PFEVQVSPEA GTQKVRAWGP GLETGQVGKS ADFVVEAIGT 600
EVGTLGFSIE GPSQAKIECD DKGDGSCDVR YWPTEPGEYA VHVICDDEDI RDSPFIAHIQ 660
PAPPDCFPDK VKAFGPGLEP TGCIVDKPAE FTIDARAAGK GDLKLYAQDA DGCPIDIKVI 720
PNGDGTFRCS YVPTKPIKHT IIISWGGVNV PKSPFRVNVG EGSHPERVKV YGPGVEKTGL 780
KANEPTYFTV DCSEAGSGDV SIGIKCAPGV VGPAEADIDF DIIKNDNDTF TVKYTPPGAG 840
HYTIMVLFAN QEIPASPFHI KVDPSHDASK VKAEGPGLNR TGVEVGKPTH FTVLTKGAGK 900
AKLDVHFAGA AKGEVVRDFE IIDNHDYSYT VKYTAVQQGN MAVTVTYGGD PVPKSPFIVN 960
VAPPLDLSKV KVQGLNSKVA VGQEQAFSVN TRGAGGQGQL DVRMTSPSRR PIPCKLEPGG 1020
GAEAQAVRYM PPEEGPYKVD ITYDGHPVPG SPFAVEGVLP PDPSKVCAYG PGLKGGLVGT 1080
PAPFSIDTKG AGTGGLGLTV EGPCEAKIEC QDNGDGSCAV SYLPTEPGEY TINILFAEAH 1140
IPGSPFKATI RPVFDPSKVR ASGPGLERGK AGEAATFTVD CSEAGEAELT IEILSDAGVK 1200
AEVLIHNNAD GTYHITYSPA FPGTYTITIK YGGHPIPKFP TRVHVQPAID TSGVKVSGPG 1260
VEPHGVLREV TTEFTVDARS LTAVGGNHVT ARVLNPSGAK TDTYVTDNGD GTYRVQYTAY 1320
EEGVHLVEVL YDEVAVPKSP FRVGVTEGCD PTRVRAFGPG LESGLVNKSN RFTVETRGAG 1380
TGGLGLAIEG PSEAKMSCKD NKDGSCTVEY IPFTPGDYDV NITFGGRPIP GSPFRVPVKD 1440
VVDPGKVKCS GPGLGAGVRA RVPQTFTVDC SQAGRAPLQV AVLSPTGVAE PVEVRDNGDG 1500
THTVHYTPAT DGPYTVAVKY ADQEVPRSPF KIKVLPAHDA SKVRASGPGL NASGIPASLP 1560
VEFTIDARDA GEGLLTVQIL DPEGKPKKAN IRDNGDGTYT VSYLPDMSGR YTITIKYGGD 1620
EIPYSPFRIH ALPTGDASKC LVTVSIGGHG LGACLGPRIQ IGEETVITVD AKAAGKGKVT 1680
CTVSTPDGAE LDVDVVENHD GTFDIYYTAP EPGKYVITIR FGGEHIPNSP FHVLACDPLP 1740
HVEEPSEVLS LRQPYTPPRP GTCPTHWATE EPVVPVEPLE SMLRPFNLVI PFTVQKGELT 1800
GEVRMPSGKT ARPNITDNKD GTITVRYAPT EKGLHQMGIK YDGNHIPGSP LQFYVDAINS 1860
RHVSAYGPGL SHGMVNKPAT FTIVTKDAGE GGLSLAVEGP SKAEITCKDN KDGTCTVSYL 1920
PTAPGDYSII VRFDDKHIPG SPFTAKITGD DSMRTSQLNV GTSTDVSLKI TESDLSLLTA 1980
SIRAPSGNEE PCLLKRLPNR HIGISFTPKE VGEHVVSVRK GGKHVTNSPF KILVGPSEIG 2040
DASKVRVWGK GLSEGHTFQV AEFIVDTRNA GYGGLGLSIE GPSKVDINCE DMEDGTCKVT 2100
YCPTEPGTYI INIKFADKHV PGSPFTVKVT GEGRMKESIT RRRQAPSIAT IGSTCDLNLK 2160
IPGNWFQMVS AQERLTRTFT RSSHTYTRTE RTEISKTRGG ETKREVRVEE STQVGGDPFP 2220
AVFGDFLGRE RLGSFGSITR QQEGEASSQD MTAQVTSPSG KTEAAEIVEG EDSAYSVRFV 2280
PQEMGPHTVT VKYRGQHVPG SPFQFTVGPL GEGGAHKVRA GGTGLERGVA GVPAEFSIWT 2340
REAGAGGLSI AVEGPSKAEI AFEDRKDGSC GVSYVVQEPG DYEVSIKFND EHIPDSPFVV 2400
PVASLSDDAR RLTVTSLQET GLKVNQPASF AVQLNGARGV IDARVHTPSG AVEECYVSEL 2460
DSDKHTIRFI PHENGVHSID VKFNGAHIPG SPFKIRVGEQ SQAGDPGLVS AYGPGLEGGT 2520
TGVSSEFIVN TLNAGSGALS VTIDGPSKVQ LDCRECPEGH VVTYTPMAPG NYLIAIKYGG 2580
PQHIVGSPFK AKVTGPRLSG GHSLHETSTV LVETVTKSSS SHGSSYSSIP KFSSDASKVV 2640
TRGPGLSQAF VGQKNSFTVD CSKAGTNMMM VGVHGPKTPC EEVYVKHIGN RVYNVTYTVK 2700
EKGDYILIVK WGDESVPGSP FKVNVP 2726 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0042383; C:sarcolemma; IEA:Compara.
 GO:0048747; P:muscle fiber development; IEA:Compara. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR001298; Filamin.
 IPR017868; Filamin/ABP280_repeat-like.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set. 
Pfam
 PF00307; CH
 PF00630; Filamin 
SMART
 SM00033; CH
 SM00557; IG_FLMN 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS50194; FILAMIN_REPEAT 
PRINTS