CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Small nuclear ribonucleoprotein component 
Protein Synonyms/Alias
  
Gene Name
 SNRP116 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
230GDIYFNPKTRKFTKKubiquitination[1]
283ELGIHLTKEELKLNIubiquitination[1]
287HLTKEELKLNIRPLLubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 GTP-binding; Nucleotide-binding; Ribonucleoprotein; Viral nucleoprotein; Virion. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 850 AA 
Protein Sequence
MDNSELIRNV TLCGHLHHGK TCFVDCLIEQ THPEIRKRYD QDLCYTDILF TEQERGVGIK 60
STPVTVVLPD TKGKSYLFNI MDTPGHVNFS DEVTAGLRIS DGVVLFIDAA EGVMLNTERL 120
IKHAVQERLA VTVCINKIDR LILELKLPPT DAYYKLRHIV DEVNGLISMY STDENLILSP 180
LLGNVCFSSS QYSICFTLGS FAKIYADTFG DINYQEFAKR LWGDIYFNPK TRKFTKKAPT 240
SSSQRSFVEF ILEPLYKILA QVVGDVDTSL PRTLDELGIH LTKEELKLNI RPLLRLVCKK 300
FFGEFTGFVD MCVQHIPSPK VGAKPKIEHT YTGGVDSDLG EAMSDCDPDG PLMCHTTKMY 360
STDDGVQFHA FGRVLSGTIH AGQPVKVLGE NYTLEDEEDS QICTVGRLWI SVARYHIEVN 420
RVPAGNWVLI EGVDQPIVKT ATITEPRGNE EAQIFRPLKF NTTSVIKIAV EPVNPSELPK 480
MLDGLRKVNK SYPSLTTKVE ESGEHVILGT GELYLDCVMH DLRKMYSEID IKVADPVVTF 540
CETVVETSSL KCFAETPNKK NKITMIAEPL EKGLAEDIEN EVVQITWNRK KLGEFFQTKY 600
DWDLLAARSI WAFGPDATGP NILVDDTLPS EVDKALLGSV KDSIVQGFQW GTREGPLCDE 660
LIRNVKFKIL DAVVAQKPLH RGGGQIIPTA RRVVYSAFLM ATPRLMEPYY FVEVQAPADC 720
VSAVYTVLAR RRGHVTQDAP IPGSPLYTIK AFIPAIDSFG FETDLRTHTQ GQAFSLSVFH 780
HWQIVPGDPL DKSIVIRPLE PQPAPHLARE FMIKTRRRKG LSEDVSISKF FDDPMLLELA 840
KQDVVLNYPM 850 
Gene Ontology
 GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:UniProtKB-KW.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR009022; EFG_III-V.
 IPR000640; EFG_V.
 IPR027417; P-loop_NTPase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
 IPR005225; Small_GTP-bd_dom.
 IPR005517; Transl_elong_EFG/EF2_IV.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00679; EFG_C
 PF03764; EFG_IV
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2 
SMART
 SM00838; EFG_C
 SM00889; EFG_IV 
PROSITE
  
PRINTS
 PR00315; ELONGATNFCT.