CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030644
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol transfer protein beta isoform 
Protein Synonyms/Alias
  
Gene Name
 PITPNB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46GEGIEVLKNEPYEKDacetylation[1]
46GEGIEVLKNEPYEKDubiquitination[2]
52LKNEPYEKDGEKGQYacetylation[3]
69KIYHLKSKVPAFVRMubiquitination[4]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 168 AA 
Protein Sequence
MGDLLMEKCR VVLPCSVQEY QVGQLYSVAE ASKNETGGGE GIEVLKNEPY EKDGEKGQYT 60
HKIYHLKSKV PAFVRMIAPE GSLVFHEKAW NAYPYCRTIV TNEYMKDDFF IKIETWHKPD 120
LGTLENVHGL DPNTWKTVEI VHIDIADRSQ VEPADYKADE DPALFQSV 168 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 
Pfam
 PF02121; IP_trans 
SMART
  
PROSITE
  
PRINTS
 PR00391; PITRANSFER.