CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011650
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosome subunit biogenesis protein NIP7 
Protein Synonyms/Alias
 Nuclear import protein 7 
Gene Name
 NIP7 
Gene Synonyms/Alias
 YPL211W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
15ETKVVFEKLAGYIGRacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly. 
Sequence Annotation
 DOMAIN 94 170 PUA.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MRQLTEEETK VVFEKLAGYI GRNISFLVDN KELPHVFRLQ KDRVYYVPDH VAKLATSVAR 60
PNLMSLGICL GKFTKTGKFR LHITSLTVLA KHAKYKIWIK PNGEMPFLYG NHVLKAHVGK 120
MSDDIPEHAG VIVFAMNDVP LGFGVSAKST SESRNMQPTG IVAFRQADIG EYLRDEDTLF 180
T 181 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0005730; C:nucleolus; TAS:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0000027; P:ribosomal large subunit assembly; TAS:SGD.
 GO:0006364; P:rRNA processing; TAS:SGD. 
Interpro
 IPR002478; PUA.
 IPR015947; PUA-like_domain.
 IPR005155; Rbsml_synth_fac_NIP7-like.
 IPR016686; Ribosomal_synth_fac_NIP7. 
Pfam
 PF03657; UPF0113 
SMART
 SM00359; PUA 
PROSITE
 PS50890; PUA 
PRINTS