CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0369 protein 
Protein Synonyms/Alias
  
Gene Name
 Dclk1 
Gene Synonyms/Alias
 Dcamkl1; mKIAA0369 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
457DGNFAVVKECIERSTubiquitination[1]
534DAITSTSKYTERDASubiquitination[1]
565NIVHRDIKPENLLVYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 791 AA 
Protein Sequence
GPAPAHQCTS GRSFQTLVLR SPSRAQPGED SSSSRPQTTQ PPPATGSISK PAMSFGRDME 60
LEHFDERDKA QRYSRGSRVN GLPSPTHSAH CSFYRTRTLQ TLSSEKKAKK VRFYRNGDRY 120
FKGIVYAISP DRFRSFEALL ADLTRTLSDN VNLPQGVRTI YTIDGLKKIS SLDQLVEGES 180
YVCGSIEPFK KLEYTKNVNP NWSVNVKTTS ASRAVSSLAT AKGGPSEVRE NKDFIRPKLV 240
TIIRSGVKPR KAVRILLNKK TAHSFEQVLT DITDAIKLDS GVVKRLYTLD GKQVMCLQDF 300
FGDDDIFIAC GPEKFRYQDD FLLDESECRV VKSTSYTKIA SASRRGTTKS PGPSRRSKSP 360
ASTSSVNGTP GSQLSTPRSG KSPSPSPTSP GSLRKQRISQ HGGSSTSLSS TKVCSSMDEN 420
DGPGEEESEE GFQIPATITE RYKVGRTIGD GNFAVVKECI ERSTAREYAL KIIKKSKCRG 480
KEHMIQNEVS ILRRVKHPNI VLLIEEMDVP TELYLVMELV KGGDLFDAIT STSKYTERDA 540
SGMLYNLASA IKYLHSLNIV HRDIKPENLL VYEHQDGSKS LKLGDFGLAT IVDGPLYTVC 600
GTPTYVAPEI IAETGYGLKV DIWAAGVITY ILLCGFPPFR GGDDQEVLFD QILMGQVDFP 660
SPYWDNVSDS AKELINMMLL VNVDQRFSAV QVLEHPWVND DGLPENEHQL SVAGKIKKHF 720
NTGPKPSSTA AGVSVIATTA LDKERQVFRR RRNQDVRSRY KAQPAPPELN SESEDYSPSS 780
SETVRSPNSP F 791 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0048675; P:axon extension; IGI:MGI.
 GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.
 GO:0048813; P:dendrite morphogenesis; IGI:MGI.
 GO:0030900; P:forebrain development; IMP:MGI.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0001764; P:neuron migration; IGI:MGI. 
Interpro
 IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
 IPR003533; Doublecortin_dom.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF03607; DCX
 PF00069; Pkinase 
SMART
 SM00537; DCX
 SM00220; S_TKc 
PROSITE
 PS50309; DC
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS