UniProt Accession

 VP26A_MOUSE; P40336; Q3TGY3; Q3THM5; Q3TW99; Q3UD54; Q8C1E9 

Genbank Protein ID

 S41204; AK028096; AK150244; AK147989; AK151360; AK159783; AK167592; AK165853; AK168213; AK168537; BC007148 

Genbank Nucleotide ID

 AAB22718.1; BAC25745.1; BAE29408.1; BAE28271.1; BAE30335.1; BAE35367.1; BAE39650.1; BAE38415.1; BAE40171.1; BAE40415.1; AAH07148.1 

Protein Name

 Vacuolar protein sorting-associated protein 26A 

Protein Synonyms/Alias

 H58 protein; H beta 58; Vesicle protein sorting 26A; mVPS26 

Gene Name

 Vps26a 

Gene Synonyms/Alias

 Vps26 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
57	GKVNLAFKQPGKRLE	ubiquitination	[1]
214	MELQLIKKEITGIGP	ubiquitination	[1]
242	IMDGAPVKGESIPIR	ubiquitination	[1]
288	EEDRRYFKQQEIILW	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). 

Sequence Annotation

 MOD_RES 315 315 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Endosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 327 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005768; C:endosome; IDA:MGI.
 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0030904; C:retromer complex; IEA:InterPro.
 GO:0031982; C:vesicle; ISS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0042147; P:retrograde transport, endosome to Golgi; IDA:MGI.
 GO:0007034; P:vacuolar transport; IEA:InterPro. 

Interpro

 IPR005377; VPS26. 

Pfam

 PF03643; Vps26 

SMART

  

PROSITE

  

PRINTS