CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026503
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA1905 protein 
Protein Synonyms/Alias
  
Gene Name
 Scin 
Gene Synonyms/Alias
 mKIAA1905 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
346TAEEFLQKMKYSTNTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 742 AA 
Protein Sequence
AVTGHRALPW AQGTDQVLGS LGQHRGTMAQ ELQHPEFARA GQQAGLQVWR VEKLELVPVP 60
QGAYGDFYVG DAYLVLHTTK SSRGFSYRLH FWLGKECSQD ESTAAAIFTV QMDDYLGGKP 120
VQSRELQGYE STDFVGYFKG GLKYKAGGVA SGLNHVLTND LTAKRLLHVK GRRVVRATEV 180
PLSWESFNKG DCFIIDLGTE IYQWCGSSCN KYERLKASQV AIGIRDNERK GRSQLIVVEE 240
GSEPSELMKV LGRKPELPDG DNDDDVVADI SNRKMAKLYM VSDASGSMKV TLVAEENPFS 300
MGMLLSEECF ILDHGAAKQI FVWKGKNANP QERKTAMKTA EEFLQKMKYS TNTQIQVLPE 360
GGETPIFKQF FKDWKDKDQS DGFGKVYITE KVAQIKQIPF DASKLHSSPQ MAAQHNMVDD 420
GSGGVEIWRV ENSGRVQIDP SSYGEFYGGD CYIILYTYPR GQIIYTWQGA NATRDELTMS 480
AFLTVQLDRS LGGQAVQVRV SQGKEPAHLL SLFKDKPLII YKNGTSKKEG QAPAPPTRLF 540
QVRRNLASIT RIVEVDVDAN SLNSNDTFVL KLPRNNGFIW IGKGASQEEE KGAEYVADVL 600
KCKASRIQEG KEPEEFWNSL GGRGDYQTSP LLETRAEDHP PRLYGCSNKT GRFIIEEVPG 660
EFTQDDLAED DVMLLDAWEQ IFIWIGKDAN EVEKKESVKS AKMYLETDPS GRDKRTPIVI 720
IKQGHEPPTF TGWFLGWDSS RW 742 
Gene Ontology
 GO:0051014; P:actin filament severing; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0045654; P:positive regulation of megakaryocyte differentiation; IEA:Compara. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR007122; Villin/Gelsolin. 
Pfam
 PF00626; Gelsolin 
SMART
 SM00262; GEL 
PROSITE
  
PRINTS
 PR00597; GELSOLIN.