| Tag | Content |
|---|
| CPLM ID | CPLM-025783 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proto-oncogene tyrosine-protein kinase LCK |
Protein Synonyms/Alias | Tyrosine-protein kinase Lck |
Gene Name | LCK |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 276 | RYYNGHTKVAVKSLK | ubiquitination | [1] | | 280 | GHTKVAVKSLKQGSM | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 516 AA |
Protein Sequence | MGCGCSSHPE DDWMENIDVC ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP 60
LQGDPRQQGL KDKACGSLAV GFHLSPTYFL PGLAFLVPHP VTPGFLPIPA RFSLMPLVFT 120
DNLVIALHSY EPSHDGDLGF EKGEQLRILE QSGEWWKAQS LTTGQEGFIP FNFVAKANSL 180
EPEPWFFKNL SRKDAERQLL APGNTHGSFL IRESESTAGS FSLSVRDFDQ NQGEVVKHYK 240
IRNLDNGGFY ISPRITFPGL HELVRHYTRY YNGHTKVAVK SLKQGSMSPD AFLAEANLMK 300
QLQHQRLVRL YAVVTQEPIY IITEYMENGS LVDFLKTPSG IKLTINKLLD MAAQIAEGMA 360
FIEERNYIHR DLRAANILVS DTLSCKIADF GLARLIEDNE YTAREGAKFP IKWTAPEAIN 420
YGTFTIKSDV WSFGILLTEI VTHGRIPYPG MTNPEVIQNL ERGYRMVRPD NCPEELYQLM 480
RLCWKERPED RPTFDYLRSV LEDFFTATEG QYQPQP 516 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |