| Tag | Content |
|---|
| CPLM ID | CPLM-014525 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Synaptic vesicle glycoprotein 2B |
Protein Synonyms/Alias | Synaptic vesicle protein 2B |
Gene Name | Sv2b |
Gene Synonyms/Alias | Sv2bb |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 341 | VFTVSHIKTPKQMDE | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Probably plays a role in the control of regulated secretion in neural and endocrine cells (By similarity). |
Sequence Annotation | REGION 486 523 BOTA-binding (By similarity).
MOD_RES 423 423 Phosphotyrosine (By similarity).
CARBOHYD 441 441 N-linked (GlcNAc...) (Potential).
CARBOHYD 491 491 N-linked (GlcNAc...) (Potential).
CARBOHYD 516 516 N-linked (GlcNAc...) (Potential). |
Keyword | Cell junction; Complete proteome; Cytoplasmic vesicle; Glycoprotein; Membrane; Neurotransmitter transport; Phosphoprotein; Receptor; Reference proteome; Synapse; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 683 AA |
Protein Sequence | MDDYRYRDNY EGYAPNDGYY RGNEQNPEED AQSDVTEGHD EEDEIYEGEY QGIPHPDDVK 60
SKQTKMAPSR ADGLRGQADL MAERMEDEEQ LAHQYETIID ECGHGRFQWT LFFVLVLALM 120
ADGVEVFVVS FALPSAEKDM CLSSSKKGML GLIVYLGMMA GAFILGGLAD KLGRKKVLSM 180
SLAINASFAS LSSFVQGYGA FLFCRLISGI GIGGSLPIVF AYFSEFLSRE KRGEHLSWLG 240
IFWMTGGIYA SAMAWSIIPH YGWGFSMGTN YHFHSWRVFV IVCALPATVS MVALKFMPES 300
PRFLLEMGKH DEAWMILKQV HDTNMRAKGT PEKVFTVSHI KTPKQMDEFI EIQSSTGTWY 360
QRWLVRFMTI FKQVWDNALY CVMGPYRMNT LILAVVWFTM ALSYYGLTVW FPDMIRYFQD 420
EEYKSKMKVF FGEHVHGATI NFTMENQIHQ HGKLVNDKFI KMYFKHVLFE DTFFDKCYFE 480
DVTSTDTYFK NCTIESTTFY NTDLYKHKFI DCRFINSTFL EQKEGCHMDF EEDNDFLIYL 540
VSFLGSLSVL PGNIISALLM DRIGRLKMIG GSMLISAVCC FFLFFGNSES AMIGWQCLFC 600
GTSIAAWNAL DVITVELYPT NQRATAFGIL NGLCKLGAIL GNTIFASFVG ITKVVPILLA 660
AASLVGGGLV ALRLPETREQ VLM 683 |
Gene Ontology | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell. GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; IDA:RGD. GO:0008021; C:synaptic vesicle; IDA:RGD. GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. GO:0022857; F:transmembrane transporter activity; IEA:InterPro. GO:0001504; P:neurotransmitter uptake; TAS:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |