CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020811
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptonemal complex central element protein 1 
Protein Synonyms/Alias
  
Gene Name
 Syce1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
101REEKVRLKDILNRKEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. 
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Chromosome; Coiled coil; Complete proteome; Meiosis; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 329 AA 
Protein Sequence
MATRPQPLGM EPEGSADLLH GPEGARGQYG STQKIEDLMD MVKKLQKVGS LEPRIEVLIN 60
RINEVQQAKK KASEELGEAQ TVWDNLQKEL DLLREEKVRL KDILNRKEET LRIMQLHCQE 120
KESEAQRKHS MLQECKERIS FLNSQIDKEK AKLRKLRLDF EEHLETLMSQ HKDTLEFHKP 180
EHLTKEMCVL DSSKEQLLKE EKLMKVKLED VRQRLCALGG PEGSSSLIEG LFLRSHEAAA 240
AMQMFKDENK KAEEFLEAAA QQHEQLQQRC HQLQQKRQRL KEELEKHGVQ ILAHSTQNEE 300
DSSWRMASPK PVEVHEETAQ DQERPSSRT 329 
Gene Ontology
 GO:0000801; C:central element; IDA:HGNC.
 GO:0005654; C:nucleoplasm; TAS:Reactome.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007130; P:synaptonemal complex assembly; IC:MGI. 
Interpro
 IPR026676; SYCE1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS